doi: 10.57264/cer-2022-0181.

Online ahead of print.


Item in Clipboard

Jean Ferrières et al.

J Comp Eff Res.



Aim: This online interactive survey investigated lipid-lowering approaches of French cardiologists in high- and very high-cardiovascular risk patients with hypercholesterolemia. Materials & methods: Physicians assessed three hypothetical patients at three clinic visits, and selected the patients’ cardiovascular risk category, target low-density lipoprotein cholesterol (LDL-C) and treatment. Results: A total of 162 physicians completed 480 risk assessments; 58% of assessments correctly categorized the hypothetical patients. Most physicians chose the correct LDL-C target for one of the very high-risk patients, but higher-than-recommended targets were selected for the other very high-risk patient and the high-risk patient. Statins were the most commonly chosen treatment. Conclusion: French cardiologists often underestimate cardiovascular risk in patients with hypercholesterolemia, select a higher-than-recommended LDL-C target and prescribe less intensive treatment than that recommended by guidelines.


France; cardiologists; cardiovascular risk; case-vignette; ezetimibe; hypercholesterolemia; lipid-lowering; online interactive survey; statin; treatment.


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Evaluation of hypercholesterolemia management in at-risk patients by cardiologists in France: a case vignette-based study

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