Case Reports

. 2022 Nov 3;36(2):224-225.

doi: 10.1080/08998280.2022.2136920.

eCollection 2023.


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Case Reports

Nitish Mittal et al.

Proc (Bayl Univ Med Cent).



Zinc phosphide toxicity is a rare entity that presents most frequently among farmers in developing countries who use it as a rodenticide. The phosphine gas released after the ingestion inhibits cytochrome c oxidase, disrupting the mitochondrial physiology and oxidative phosphorylation and causing myocardial stunning. Here we present a case of a 20-year-old man who attempted suicide with zinc phosphide toxicity. Initially, he was hemodynamically stable with a normal ejection fraction; however, in a few hours, he deteriorated quickly and became hemodynamically unstable, with rapid deterioration of his ejection fraction to 20%. He was started on norepinephrine and then dobutamine; however, he had cardiac arrest from refractory cardiogenic shock despite resuscitative measures.


Cardiogenic shock; metal phosphides; zinc phosphide.

Conflict of interest statement

The authors report no funding or conflicts of interest. The patient gave permission for the case to be published.


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Refractory cardiogenic shock caused by zinc phosphide toxicity

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