Jianning Zhang | Atherosclerosis | Best Researcher Award

Prof. Jianning Zhang | Atherosclerosis | Best Researcher Award

Chinese PLA General Hospital | China

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🧠🌟 ICON OF NEUROSURGERY: PROFESSOR JIANNING ZHANG 🌟🧠

🎓 EARLY ACADEMIC PURSUITS

Professor Jianning Zhang began his medical journey driven by a profound interest in neurological sciences. His early academic endeavors built a solid foundation, enabling him to become a future leader in neurosurgery. Through diligent study, clinical excellence, and deep curiosity, he prepared himself to tackle the most complex challenges in brain and spinal surgery.

🏥 PROFESSIONAL ENDEAVORS

Prof. Zhang currently serves as the Director of the Department of Neurosurgery at PLA General Hospital . Holding the military rank of Major General (Professional Technical) , he is a respected Chief Physician, Professor, and Doctoral Supervisor .

Key Leadership Roles:

  • Chairman, Neurotrauma Branch, China International Exchange and Promotive Association for Medical and Health Care

  • Vice Chairman, Neurosurgery Professional Committee of the PLA

  • Associate Editor, Medical Journal of Chinese People's Liberation Army & Journal of Clinical Neurosurgery

  • Editorial Board Member, 10+ journals including Chinese Journal of Neurosurgery

His professional presence bridges clinical care, academic scholarship, and military medical advancement.

🔬 CONTRIBUTIONS AND RESEARCH FOCUS ON ATHEROSCLEROSIS

A true innovator in neurotrauma and surgical science, Prof. Zhang has led over 20 major research projects, including:

  • National 863 Program Projects

  • Military Logistics Research Projects

  • National Natural Science Foundation Projects

  • Beijing Capital Characteristic Clinical Projects

Surgical Specialties:

  • Minimally invasive microsurgery

  • Neuronavigation-guided procedures

  • Brainstem tumors

  • Skull base tumors

  • Craniocervical junction malformations

  • Cavernous sinus tumors

  • Intracranial aneurysms

  • Cerebral AVMs

  • Intramedullary spinal cord tumors

🏆 IMPACT AND INFLUENCE

Prof. Zhang’s impact is reflected through numerous national and institutional honors:

Awards & Honors:

  • National Science and Technology Progress Award (Second Class)

  • Chinese Medical Science and Technology Award (First Class)

  • PLA Science and Technology Progress Awards (First & Second Class)

Special Recognitions:

  • Wang Zhongcheng Academic Achievement Award in Neurosurgery (2014)

  • National “Bethune-Style Good Doctor” (4th Session, 2020)

  • “People’s Renowned Doctor • Outstanding Contribution” (2022)

He also receives special government allowances from the State Council and first-class technical cadre allowances from the PLA.

📚 ACADEMIC CITES & SCHOLARLY WORK

As a prolific researcher, Prof. Zhang has published over 300 academic papers , primarily as first or corresponding author. His contributions are widely cited across neurosurgical research, shaping both clinical guidelines and surgical innovations.

His editorial roles and research citations place him among the most respected academic voices in neurosurgery across China and internationally.

🌍 LEGACY AND FUTURE CONTRIBUTIONS

Prof. Jianning Zhang’s work continues to inspire future generations of neurosurgeons, educators, and researchers. His legacy is one of innovation, leadership, and service to humanity and national health development.

As he continues to shape the future of neurosurgery, his dedication to research and patient care remains unwavering — ensuring safer, more effective treatments for even the most complex neurological disorders.

📑 NOTABLE PUBLICATIONS

"The Transtemporal Isthmus Approach for Insular Glioma Surgery"

Authors: G Sun, X Shu, D Wu, K Zhao, Z Xue, G Cheng, L Chen, J Zhang
Journal: Operative Neurosurgery
Year: 2025

"Impact of celastrol on mitochondrial dynamics and proliferation in glioblastoma"

Authors: L Liang, W Lv, G Cheng, M Gao, J Sun, N Liu, H Zhang, B Guo, J Liu, Y Li, S Xie, J Wang
Journal: BMC Cancer
Year: 2025

Zhuofeng Lin | Myocardial infarction | Best Researcher Award

Prof. Dr. Zhuofeng Lin | Myocardial infarction | Best Researcher Award 

Prof. Dr. Zhuofeng Lin, Guangdong Medical University, China

Prof. Dr. Zhuofeng Lin is the Dean of the Experimental Animal Center and Dean of the Innovational Center of Cardiometabolic Disease at Guangdong Medical University, China. His research focuses on cross-organ communication in cardiovascular and metabolic diseases, particularly the role of metabolic hormones and obesity. He has made significant contributions to understanding FGF21 metabolic regulation, impacting blood glucose stability, blood pressure control, and anti-atherosclerosis therapies. His work also explores new targets for anti-myocardial infarction, heart failure, and vascular calcification drugs, driving innovation in metabolic and cardiovascular medicine. His research is widely recognized in international medical science.

AUTHOR PROFILE

Google Scholar Profile

🎓EARLY ACADEMIC PURSUITS:

Prof. Dr. Zhuofeng Lin’s academic journey began with a strong foundation in medical sciences, focusing on cardiovascular and metabolic diseases. His early research explored physiological mechanisms and metabolic interactions, leading him to specialize in cross-organ communication and metabolic regulation. His education and initial training laid the groundwork for his extensive contributions to cardiometabolic research.

🏢PROFESSIONAL ENDEAVORS:

Prof. Lin has held prestigious positions at Guangdong Medical University, where he currently serves as:

  • Dean of the Experimental Animal Center 🐁
  • Dean of the Innovational Center of Cardiometabolic Disease 🫀

His leadership in these institutions has driven significant advancements in experimental research methodologies and the development of innovative treatment strategies for metabolic disorders.

🔍CONTRIBUTIONS AND RESEARCH FOCUS ON MYOCARDIAL INFARCTION:

Prof. Lin’s research is dedicated to practical applications, with a strong emphasis on:

  • Cross-organ communication in cardiovascular and metabolic diseases
  • Pathogenesis of cardiometabolic disorders linked to metabolic hormones and obesity
  • Fibroblast Growth Factor 21 (FGF21) and its role in metabolic regulation

His studies have provided groundbreaking insights into FGF21’s ability to regulate:
Blood glucose levels
Blood pressure stability
Anti-atherosclerosis mechanisms
Anti-Metabolic Dysfunction-Associated Steatohepatitis (MASH) therapies

Additionally, his work focuses on discovering new therapeutic targets for:
⚕️ Anti-myocardial infarction drugs
⚕️ Anti-heart failure treatments
⚕️ Anti-vascular calcification solutions

🌍IMPACT AND INFLUENCE:

Prof. Lin’s research has had a profound impact on global medical science, particularly in the fields of:
🔹 Metabolic disease management
🔹 Cardiovascular treatment innovations
🔹 Therapeutic drug development

His studies have influenced clinical practices, contributing to better patient outcomes in cardiovascular and metabolic health. His pioneering work in hormonal regulation and metabolic stability has inspired numerous scientists and researchers worldwide.

📄ACADEMIC CITES AND RECOGNITION:

Prof. Lin’s research is widely recognized in high-impact medical journals, with numerous citations supporting his theories. His work on FGF21 metabolic regulation is frequently referenced in the fields of endocrinology, cardiology, and metabolic research. He has been a keynote speaker at international medical conferences, sharing his insights with the global scientific community.

🚀LEGACY AND FUTURE CONTRIBUTIONS:

With an unwavering commitment to scientific innovation, Prof. Lin continues to shape the future of medical research. His ongoing projects aim to:
🔬 Develop novel cardiometabolic therapies
🔬 Enhance cross-organ communication research
🔬 Introduce cutting-edge treatments for heart disease and metabolic disorders

His legacy will be defined by his transformative contributions to medicine, paving the way for future breakthroughs in cardiovascular and metabolic health.

💡CONCLUSION:

Prof. Dr. Zhuofeng Lin is a pioneering leader in cardiometabolic research, making groundbreaking contributions to understanding metabolic regulation and cardiovascular health. His work on FGF21 has revolutionized approaches to blood glucose stability, blood pressure control, and anti-atherosclerosis treatments . With a vision for therapeutic innovation, he continues to explore new drug targets for heart failure, myocardial infarction, and vascular calcification . His impact on medical science is profound, shaping the future of metabolic and cardiovascular treatments. His dedication ensures lasting advancements in healthcare and patient well-being.

TOP NOTABLE PUBLICATIONS

Adiponectin mediates the metabolic effects of FGF21 on glucose homeostasis and insulin sensitivity in mice

Authors: Z Lin, H Tian, KSL Lam, S Lin, RCL Hoo, M Konishi, N Itoh, Y Wang, …
Journal: Cell Metabolism
Year: 2013

Fibroblast growth factor 21 prevents atherosclerosis by suppression of hepatic sterol regulatory element-binding protein-2 and induction of adiponectin in mice

Authors: Z Lin, X Pan, F Wu, D Ye, Y Zhang, Y Wang, L Jin, Q Lian, Y Huang, …
Journal: Circulation
Year: 2015

Serum levels of FGF-21 are increased in coronary heart disease patients and are independently associated with adverse lipid profile

Authors: Z Lin, Z Wu, X Yin, Y Liu, X Yan, S Lin, J Xiao, X Wang, W Feng, X Li
Journal: PLoS One
Year: 2010

Exercise alleviates obesity-induced metabolic dysfunction via enhancing FGF21 sensitivity in adipose tissues

Authors: L Geng, B Liao, L Jin, Z Huang, CR Triggle, H Ding, J Zhang, Y Huang, …
Journal: Cell Reports
Year: 2019

Lipocalin-2 mediates non-alcoholic steatohepatitis by promoting neutrophil-macrophage crosstalk via the induction of CXCR2

Authors: D Ye, K Yang, S Zang, Z Lin, HT Chau, Y Wang, J Zhang, J Shi, A Xu, …
Journal: Journal of Hepatology
Year: 2016

Circulating FGF21 levels are progressively increased from the early to end stages of chronic kidney diseases and are associated with renal function in Chinese

Authors: Z Lin, Z Zhou, Y Liu, Q Gong, X Yan, J Xiao, X Wang, S Lin, W Feng, X Li
Journal: PLoS One
Year: 2011

FGF21 prevents angiotensin II-induced hypertension and vascular dysfunction by activation of ACE2/angiotensin-(1–7) axis in mice

Authors: X Pan, Y Shao, F Wu, Y Wang, R Xiong, J Zheng, H Tian, B Wang, …
Journal: Cell Metabolism
Year: 2018

Adiponectin protects against acetaminophen-induced mitochondrial dysfunction and acute liver injury by promoting autophagy in mice

Authors: Z Lin, F Wu, S Lin, X Pan, L Jin, T Lu, L Shi, Y Wang, A Xu, X Li
Journal: Journal of Hepatology
Year: 2014

Pancreatic fibroblast growth factor 21 protects against type 2 diabetes in mice by promoting insulin expression and secretion in a PI3K/Akt signaling‐dependent manner

Authors: Y Pan, B Wang, J Zheng, R Xiong, Z Fan, Y Ye, S Zhang, Q Li, F Gong, …
Journal: Journal of Cellular and Molecular Medicine
Year: 2019

Dynamic change of serum FGF21 levels in response to glucose challenge in human

Authors: Z Lin, Q Gong, C Wu, J Yu, T Lu, X Pan, S Lin, X Li
Journal: The Journal of Clinical Endocrinology & Metabolism
Year: 2012