Zhuofeng Lin | Myocardial infarction | Best Researcher Award

Posted on 25/02/202525/02/2025 by Pencis

Prof. Dr. Zhuofeng Lin | Myocardial infarction | Best Researcher Award

Prof. Dr. Zhuofeng Lin, Guangdong Medical University, China

Prof. Dr. Zhuofeng Lin is the Dean of the Experimental Animal Center and Dean of the Innovational Center of Cardiometabolic Disease at Guangdong Medical University, China. His research focuses on cross-organ communication in cardiovascular and metabolic diseases, particularly the role of metabolic hormones and obesity. He has made significant contributions to understanding FGF21 metabolic regulation, impacting blood glucose stability, blood pressure control, and anti-atherosclerosis therapies. His work also explores new targets for anti-myocardial infarction, heart failure, and vascular calcification drugs, driving innovation in metabolic and cardiovascular medicine. His research is widely recognized in international medical science.

AUTHOR PROFILE

Google Scholar Profile

🎓EARLY ACADEMIC PURSUITS:

Prof. Dr. Zhuofeng Lin’s academic journey began with a strong foundation in medical sciences, focusing on cardiovascular and metabolic diseases. His early research explored physiological mechanisms and metabolic interactions, leading him to specialize in cross-organ communication and metabolic regulation. His education and initial training laid the groundwork for his extensive contributions to cardiometabolic research.

🏢PROFESSIONAL ENDEAVORS:

Prof. Lin has held prestigious positions at Guangdong Medical University, where he currently serves as:

Dean of the Experimental Animal Center 🐁
Dean of the Innovational Center of Cardiometabolic Disease 🫀

His leadership in these institutions has driven significant advancements in experimental research methodologies and the development of innovative treatment strategies for metabolic disorders.

🔍CONTRIBUTIONS AND RESEARCH FOCUS ON MYOCARDIAL INFARCTION:

Prof. Lin’s research is dedicated to practical applications, with a strong emphasis on:

Cross-organ communication in cardiovascular and metabolic diseases
Pathogenesis of cardiometabolic disorders linked to metabolic hormones and obesity
Fibroblast Growth Factor 21 (FGF21) and its role in metabolic regulation

His studies have provided groundbreaking insights into FGF21’s ability to regulate:
✅ Blood glucose levels
✅ Blood pressure stability
✅ Anti-atherosclerosis mechanisms
✅ Anti-Metabolic Dysfunction-Associated Steatohepatitis (MASH) therapies

Additionally, his work focuses on discovering new therapeutic targets for:
⚕️ Anti-myocardial infarction drugs
⚕️ Anti-heart failure treatments
⚕️ Anti-vascular calcification solutions

🌍IMPACT AND INFLUENCE:

Prof. Lin’s research has had a profound impact on global medical science, particularly in the fields of:
🔹 Metabolic disease management
🔹 Cardiovascular treatment innovations
🔹 Therapeutic drug development

His studies have influenced clinical practices, contributing to better patient outcomes in cardiovascular and metabolic health. His pioneering work in hormonal regulation and metabolic stability has inspired numerous scientists and researchers worldwide.

📄ACADEMIC CITES AND RECOGNITION:

Prof. Lin’s research is widely recognized in high-impact medical journals, with numerous citations supporting his theories. His work on FGF21 metabolic regulation is frequently referenced in the fields of endocrinology, cardiology, and metabolic research. He has been a keynote speaker at international medical conferences, sharing his insights with the global scientific community.

🚀LEGACY AND FUTURE CONTRIBUTIONS:

With an unwavering commitment to scientific innovation, Prof. Lin continues to shape the future of medical research. His ongoing projects aim to:
🔬 Develop novel cardiometabolic therapies
🔬 Enhance cross-organ communication research
🔬 Introduce cutting-edge treatments for heart disease and metabolic disorders

His legacy will be defined by his transformative contributions to medicine, paving the way for future breakthroughs in cardiovascular and metabolic health.

💡CONCLUSION:

Prof. Dr. Zhuofeng Lin is a pioneering leader in cardiometabolic research, making groundbreaking contributions to understanding metabolic regulation and cardiovascular health. His work on FGF21 has revolutionized approaches to blood glucose stability, blood pressure control, and anti-atherosclerosis treatments . With a vision for therapeutic innovation, he continues to explore new drug targets for heart failure, myocardial infarction, and vascular calcification . His impact on medical science is profound, shaping the future of metabolic and cardiovascular treatments. His dedication ensures lasting advancements in healthcare and patient well-being.

TOP NOTABLE PUBLICATIONS

Adiponectin mediates the metabolic effects of FGF21 on glucose homeostasis and insulin sensitivity in mice

Authors: Z Lin, H Tian, KSL Lam, S Lin, RCL Hoo, M Konishi, N Itoh, Y Wang, …
Journal: Cell Metabolism
Year: 2013

Fibroblast growth factor 21 prevents atherosclerosis by suppression of hepatic sterol regulatory element-binding protein-2 and induction of adiponectin in mice

Authors: Z Lin, X Pan, F Wu, D Ye, Y Zhang, Y Wang, L Jin, Q Lian, Y Huang, …
Journal: Circulation
Year: 2015

Serum levels of FGF-21 are increased in coronary heart disease patients and are independently associated with adverse lipid profile

Authors: Z Lin, Z Wu, X Yin, Y Liu, X Yan, S Lin, J Xiao, X Wang, W Feng, X Li
Journal: PLoS One
Year: 2010

Exercise alleviates obesity-induced metabolic dysfunction via enhancing FGF21 sensitivity in adipose tissues

Authors: L Geng, B Liao, L Jin, Z Huang, CR Triggle, H Ding, J Zhang, Y Huang, …
Journal: Cell Reports
Year: 2019

Lipocalin-2 mediates non-alcoholic steatohepatitis by promoting neutrophil-macrophage crosstalk via the induction of CXCR2

Authors: D Ye, K Yang, S Zang, Z Lin, HT Chau, Y Wang, J Zhang, J Shi, A Xu, …
Journal: Journal of Hepatology
Year: 2016

Circulating FGF21 levels are progressively increased from the early to end stages of chronic kidney diseases and are associated with renal function in Chinese

Authors: Z Lin, Z Zhou, Y Liu, Q Gong, X Yan, J Xiao, X Wang, S Lin, W Feng, X Li
Journal: PLoS One
Year: 2011

FGF21 prevents angiotensin II-induced hypertension and vascular dysfunction by activation of ACE2/angiotensin-(1–7) axis in mice

Authors: X Pan, Y Shao, F Wu, Y Wang, R Xiong, J Zheng, H Tian, B Wang, …
Journal: Cell Metabolism
Year: 2018

Adiponectin protects against acetaminophen-induced mitochondrial dysfunction and acute liver injury by promoting autophagy in mice

Authors: Z Lin, F Wu, S Lin, X Pan, L Jin, T Lu, L Shi, Y Wang, A Xu, X Li
Journal: Journal of Hepatology
Year: 2014

Pancreatic fibroblast growth factor 21 protects against type 2 diabetes in mice by promoting insulin expression and secretion in a PI3K/Akt signaling‐dependent manner

Authors: Y Pan, B Wang, J Zheng, R Xiong, Z Fan, Y Ye, S Zhang, Q Li, F Gong, …
Journal: Journal of Cellular and Molecular Medicine
Year: 2019

Dynamic change of serum FGF21 levels in response to glucose challenge in human

Authors: Z Lin, Q Gong, C Wu, J Yu, T Lu, X Pan, S Lin, X Li
Journal: The Journal of Clinical Endocrinology & Metabolism
Year: 2012

Songyun Wang | Arrhythmia | Best Researcher Award

Posted on 25/01/202525/01/2025 by Pencis

Dr. Songyun Wang | Arrhythmia | Best Researcher Award

Dr. Songyun Wang, Department of Cardiology, Renmin Hospital of Wuhan University, Wuhan, China

Dr. Songyun Wang is an Associate Professor and Associate Chief Physician at the Department of Cardiology, Renmin Hospital of Wuhan University, China. He holds a B.S. in Medicine, a Ph.D. in Internal Medicine from Wuhan University, and a joint Ph.D. in Cardiovascular Disease from Mayo Medical Center, USA. With expertise in neuromodulation, neuroinflammation, and cardiovascular diseases, Dr. Wang has undertaken 24 scientific foundations and published over 60 high-impact SCI articles, including 24 as the first or corresponding author. His groundbreaking research on noninvasive neuromodulation for preventing cardiac arrhythmias highlights his commitment to advancing patient care and clinical innovation.

Author Profile

Scopus Profile

Orcid Profile

🎓EARLY ACADEMIC PURSUITS:

Dr. Songyun Wang embarked on an exceptional academic journey by earning a Bachelor of Science in Medicine and a Ph.D. in Internal Medicine from the First Clinical College of Wuhan University, China. He further broadened his academic foundation through a joint Ph.D. in Cardiovascular Disease at the prestigious Mayo Medical Center in the USA. This diverse and rigorous training laid the groundwork for his expertise in cardiology and innovative research methodologies.

🩺PROFESSIONAL ENDEAVORS:

Currently serving as an Associate Professor and Associate Chief Physician at the Department of Cardiology, Renmin Hospital of Wuhan University, Dr. Wang has cemented his reputation as a key figure in cardiovascular medicine. He has been an active participant and leader in 24 scientific foundations, showcasing his dedication to advancing the field. His professional responsibilities blend clinical excellence and research innovation, reflecting his commitment to improving patient care.

🔬CONTRIBUTIONS AND RESEARCH FOCUS ON ARRHYTHMIA:

Dr. Wang’s research is centered on neuromodulation, neuroinflammation, and cardiovascular disease. His contributions include groundbreaking insights into the relationship between neuroinflammation and cardiovascular conditions. One of his notable achievements is the study of noninvasive low-intensity focused ultrasound neuromodulation, which has been shown to effectively prevent cardiac arrhythmias. This work has garnered significant attention and holds transformative potential for clinical applications.

🌍IMPACT AND INFLUENCE:

Dr. Wang’s prolific publication record includes over 60 high-impact SCI articles, with 24 as the first or corresponding author. His research has been widely cited and serves as a foundation for further studies in cardiovascular disease. By addressing critical gaps in knowledge and proposing innovative therapeutic strategies, Dr. Wang has become a beacon of inspiration for his peers and the next generation of researchers.

📚ACADEMIC CITATIONS:

Dr. Wang’s work has been extensively referenced in both clinical and academic circles, underscoring its importance and relevance. His studies on neuromodulation and autonomic regulation in cardiac arrhythmias are frequently cited as pioneering contributions to the field of cardiology.

🌟LEGACY AND FUTURE CONTRIBUTIONS:

Dr. Wang is deeply committed to the clinical translation of neuromodulation techniques, ensuring that his research directly benefits patients with arrhythmias. His vision for the future involves refining these technologies and expanding their accessibility to a broader patient population. His dedication to both innovation and patient care ensures that his legacy will resonate in the medical community for years to come.

🏆OTHER IMPORTANT HIGHLIGHTS:

Interdisciplinary Collaboration: Dr. Wang’s joint Ph.D. at Mayo Medical Center demonstrates his ability to work across borders and institutions to achieve groundbreaking results.
Clinical Relevance: His focus on translational research bridges the gap between laboratory discoveries and real-world patient care.
Inspiration to Peers: Dr. Wang’s leadership in 24 scientific foundations reflects his role as a mentor and guide to fellow researchers.

✨CONCLUSION:

Dr. Songyun Wang exemplifies the qualities of a visionary researcher, dedicated educator, and compassionate physician. His outstanding academic credentials, innovative contributions, and commitment to advancing cardiovascular medicine make him a deserving candidate for the Best Researcher Award. Through his work, Dr. Wang continues to inspire and elevate the global standard of cardiology research and practice.

TOP NOTABLE PUBLICATIONS

An Ultrasound-Activated Supramolecular Modulator Enhancing Autophagy to Prevent Ventricular Arrhythmias Post-Myocardial Infarction

Authors: Pang, Y., Li, Q., Wang, J., Liu, S., Sun, Y.

Journal: Angewandte Chemie – International Edition

Year: 2025

Noninvasive Oral Hyperspectral Imaging–Driven Digital Diagnosis of Heart Failure With Preserved Ejection Fraction: Model Development and Validation Study

Authors: Yang, X., Li, Z., Lei, L., Zhong, Y., Yu, L.

Journal: Journal of Medical Internet Research

Year: 2025

Potential Microemboli Formation Risk and Its Management During the Heated Saline–Enhanced Radiofrequency Needle-Tip Catheter Ablation

Authors: Suzuki, A., Lehmann, H.I., Konishi, H., Curley, M.G., Packer, D.L.

Journal: Heart Rhythm

Year: 2024

Wearable Ultrasound Devices: An Emerging Era for Biomedicine and Clinical Translation

Authors: Hu, H., Hu, C., Guo, W., Zhu, B., Wang, S.

Journal: Ultrasonics

Year: 2024

Subarachnoid Haemorrhage-Induced Reversible Cardiac Dysfunction: Time Course and Potential Mechanisms

Authors: Xiao, Y., Lai, X., Wang, Z., Chen, M., Zhou, S.

Journal: ESC Heart Failure

Year: 2024

Low-Intensity Focused Ultrasound Modulation of the Paraventricular Nucleus to Prevent Myocardial Infarction–Induced Ventricular Arrhythmia

Authors: Xiang, C., Cheng, Y., Yu, X., Wang, S., Jiang, H.

Journal: Heart Rhythm

Year: 2024

Efficacy, Safety, and Somatosensory Comparison of Pulsed-Field Ablation and Thermal Ablation: Outcomes From a 2-Year Follow-Up

Authors: Wang, J., Wang, X., Liu, W., Wang, S., Jiang, H.

Journal: Journal of Interventional Cardiac Electrophysiology

Year: 2024

Long-Term Transcranial Ultrasound Stimulation Regulates Neuroinflammation to Ameliorate Post–Myocardial Infarction Cardiac Arrhythmia and Remodeling

Authors: Hu, H., Wu, H., Zhu, T., Jiang, H., Wang, S.

Journal: Heart Rhythm

Year: 2024

Emerging Near-Infrared Targeting Diagnostic and Therapeutic Strategies for Ischemic Cardiovascular and Cerebrovascular Diseases

Authors: Yu, M., Wu, H., Hu, H., Jiang, H., Wang, S.

Journal: Acta Biomaterialia

Year: 2024

Mitochondria-Targeted Sonodynamic Modulation of Neuroinflammation to Protect Against Myocardial Ischemia–Reperfusion Injury

Authors: Hu, H., Li, Q., Wang, J., Sun, Y., Wang, S.

Journal: Acta Biomaterialia

Year: 2024

XIngcheng Yi | Myocardial tissue repair | Best Researcher Award

Posted on 28/11/202428/11/2024 by Pencis

Dr. XIngcheng Yi | Myocardial tissue repair | Best Researcher Award

Dr. XIngcheng Yi, The First Hospital of Jilin University, China

🌟Profile Overview:

Dr. Xingcheng Yi is a distinguished medical professional at The First Hospital of Jilin University, China, specializing in cutting-edge clinical and translational research. With a strong focus on advancing patient care, Dr. Yi’s expertise spans cardiovascular medicine, oncology, and innovative therapeutic approaches. A dedicated scholar and practitioner, Dr. Yi is actively involved in groundbreaking studies, contributing to the global medical community through peer-reviewed publications and collaborative projects. Known for integrating clinical insights with advanced research, Dr. Yi’s work continues to impact healthcare practices and improve outcomes for patients worldwide.

Profile:

Scopus Profile

🎓Current Position:

Currently serving as a lead researcher in Cell Biology, my work focuses on innovative therapeutic strategies for myocardial tissue repair. Leveraging expertise in computational biology, I aim to bridge experimental and computational sciences to drive impactful discoveries in cardiovascular health.

📚Academic Background:

Earned a Ph.D. in Cell Biology, with a thesis focused on molecular interaction networks in myocardial injury.
Prior to this, completed a Master’s in Biological Sciences, specializing in cellular mechanisms and computational applications.

📝Publications Achievements:

Publications: Authored 11 peer-reviewed journal articles, indexed in SCI and Scopus, spanning myocardial repair, single-cell transcriptomics, and graph deep learning.
Books: Published 11 books with ISBN registration, contributing to knowledge dissemination in cell biology and computational techniques.
Citations: Achieved a citation index of 18, demonstrating the growing influence of my research in the academic community.
Recognized for a recent impactful study on Ginsenoside Rb1 and PRDX6 in mitigating myocardial injury.

🔬Ongoing Research Projects:

Current Projects: Actively involved in three research projects, focusing on:

Synergistic Therapies: Examining natural compounds and molecular interactions for cardiac protection.
Transcriptomics: Exploring gene expression changes linked to tissue repair and cellular stress responses.
Graph-Based Models: Developing AI-based models to predict molecular interaction networks and their biological implications.

Collaborations: Engaged in interdisciplinary collaborations with computational scientists and clinical researchers to validate models in vivo.

🔍Research Interests:

Areas of expertise and passion include:

Myocardial Tissue Repair: Exploring cellular mechanisms to improve heart regeneration.
Single-Cell Transcriptomics: Unraveling cellular diversity and gene expression.
Graph Deep Learning: Applying cutting-edge computational tools for network analysis.
Bioinformatics: Leveraging data-driven approaches to solve biological challenges.

🏆Awards and Scholarships:

Recipient of multiple awards for research excellence, including the prestigious Best Researcher Award for groundbreaking work in myocardial repair.
Secured competitive scholarships during doctoral studies, highlighting academic rigor and potential.

🎤Professional Associations:

Active member of professional societies like the Society for Computational Biology and the American Heart Association, contributing to global discussions on translational research.

🎓Training & Workshops:

Participated in numerous workshops on advanced computational techniques, transcriptomics, and bioinformatics.
Conducted training sessions for peers, fostering skills in RNA-seq analysis and molecular modeling.

🧪Laboratory Experience and Publications:

Proficient in wet lab techniques such as immunohistochemistry, PCR, and cell culture, complemented by computational methods like network analysis and deep learning models.
Authored comprehensive reports and proposals that secured funding for cutting-edge research.

🛠️Tasks Completed as a Researcher:

Designed and executed experiments involving RNA sequencing and gene expression profiling.
Supervised lab teams in handling complex protocols for tissue repair studies.
Published high-impact manuscripts, showcasing methodological rigor and innovative findings.

🎤Oral Presentations:

Delivered over 15 oral presentations at national and international conferences, including keynote sessions on myocardial repair strategies.
Topics included novel therapeutic combinations and advancements in single-cell analysis.

🌟Success Factors:

My success stems from a combination of interdisciplinary expertise, strong analytical skills, and an unwavering commitment to advancing cardiovascular science.
Emphasis on collaboration ensures that my research remains globally relevant and impactful.

🌍Conclusion:

My journey as a researcher is defined by a relentless drive to innovate in myocardial tissue repair and computational biology. By integrating biological insights with computational tools, I aim to pave the way for new therapeutic solutions that save lives. From groundbreaking publications to collaborative projects, my work continues to contribute meaningfully to science and society.

Top Notable Publications:

Article: Hypoxia adaptation mechanism in rats’ peripheral auditory system in high altitude migration: a time series transcriptome analysis
Authors: Wang, L., Yi, X., Zhou, Y., Su, X., Wang, P.
Year: 2024
Journal: Scientific Reports
Citations: 0

Letter: Individualized dynamic frailty-tailored therapy (DynaFiT) in elderly patients with newly diagnosed multiple myeloma: a prospective study
Authors: Zhang, Y., Liang, X., Xu, W., Dai, Y., Jin, F.
Year: 2024
Journal: Journal of Hematology and Oncology
Citations: 1

Article: Dynamics of minimal residual disease and its clinical implications in multiple myeloma: A retrospective real-life analysis
Authors: Xu, W., Liang, X., Liu, S., Dai, Y., Jin, F.
Year: 2024
Journal: Clinical Medicine, Journal of the Royal College of Physicians of London
Citations: 0

Article: Plumbagin induces G2/M arrest and apoptosis and ferroptosis via ROS/p38 MAPK pathway in human osteosarcoma cells
Authors: Li, J., Gao, H., Wang, P., Zhang, Y., Li, S.
Year: 2024
Journal: Alexandria Engineering Journal
Citations: 1

Article: MediDRNet: Tackling category imbalance in diabetic retinopathy classification with dual-branch learning and prototypical contrastive learning
Authors: Teng, S., Wang, B., Yang, F., Zhang, X., Sun, Y.
Year: 2024
Journal: Computer Methods and Programs in Biomedicine
Citations: 0

Article in Press: Synergistic effects of ginsenoside Rb1 and peroxiredoxin 6 in enhancing myocardial injury treatment through anti-inflammatory, anti-oxidative, and anti-apoptotic mechanisms
Authors: Mu, R., Li, Y., Cui, Y., Guo, X., Yi, X.
Year: 2024
Journal: Journal of Ginseng Research
Citations: 0

Letter: More than 2% circulating plasma cells as a prognostic biomarker in a large cohort of patients with newly-diagnosed multiple myeloma
Authors: Tian, M., Liang, X., Xu, W., Dai, Y., Jin, F.
Year: 2023
Journal: Annals of Hematology
Citations: 0

Letter: Dynamic monitoring of minimal residual disease in newly-diagnosed multiple myeloma
Authors: Yang, P., Xu, W., Liang, X., Dai, Y., Jin, F.
Year: 2023
Journal: American Journal of Hematology
Citations: 3

Article: Proposed risk-scoring model for estimating the prognostic impact of 1q gain in patients with newly diagnosed multiple myeloma
Authors: Yang, P., Chen, H., Liang, X., Dai, Y., Jin, F.
Year: 2023
Journal: American Journal of Hematology
Citations: 7

Article: Research on the pathological mechanism of rectal adenocarcinoma based on DNA methylation
Authors: Pan, X., Yi, X., Lan, M., Zhou, F., Wu, W.
Year: 2023
Journal: Medicine (United States)
Citations: 2