XIngcheng Yi | Myocardial tissue repair | Best Researcher Award

🎓Current Position:

Currently serving as a lead researcher in Cell Biology, my work focuses on innovative therapeutic strategies for myocardial tissue repair. Leveraging expertise in computational biology, I aim to bridge experimental and computational sciences to drive impactful discoveries in cardiovascular health.

📚Academic Background:

Earned a Ph.D. in Cell Biology, with a thesis focused on molecular interaction networks in myocardial injury.
Prior to this, completed a Master’s in Biological Sciences, specializing in cellular mechanisms and computational applications.

📝Publications Achievements:

Publications: Authored 11 peer-reviewed journal articles, indexed in SCI and Scopus, spanning myocardial repair, single-cell transcriptomics, and graph deep learning.
Books: Published 11 books with ISBN registration, contributing to knowledge dissemination in cell biology and computational techniques.
Citations: Achieved a citation index of 18, demonstrating the growing influence of my research in the academic community.
Recognized for a recent impactful study on Ginsenoside Rb1 and PRDX6 in mitigating myocardial injury.

🔬Ongoing Research Projects:

Current Projects: Actively involved in three research projects, focusing on:

  1. Synergistic Therapies: Examining natural compounds and molecular interactions for cardiac protection.
  2. Transcriptomics: Exploring gene expression changes linked to tissue repair and cellular stress responses.
  3. Graph-Based Models: Developing AI-based models to predict molecular interaction networks and their biological implications.

Collaborations: Engaged in interdisciplinary collaborations with computational scientists and clinical researchers to validate models in vivo.

🔍Research Interests:

Areas of expertise and passion include:

  • Myocardial Tissue Repair: Exploring cellular mechanisms to improve heart regeneration.
  • Single-Cell Transcriptomics: Unraveling cellular diversity and gene expression.
  • Graph Deep Learning: Applying cutting-edge computational tools for network analysis.
  • Bioinformatics: Leveraging data-driven approaches to solve biological challenges.

🏆Awards and Scholarships:

Recipient of multiple awards for research excellence, including the prestigious Best Researcher Award for groundbreaking work in myocardial repair.
Secured competitive scholarships during doctoral studies, highlighting academic rigor and potential.

🎤Professional Associations:

Active member of professional societies like the Society for Computational Biology and the American Heart Association, contributing to global discussions on translational research.

🎓Training & Workshops: 

Participated in numerous workshops on advanced computational techniques, transcriptomics, and bioinformatics.
Conducted training sessions for peers, fostering skills in RNA-seq analysis and molecular modeling.

🧪Laboratory Experience and Publications: 

Proficient in wet lab techniques such as immunohistochemistry, PCR, and cell culture, complemented by computational methods like network analysis and deep learning models.
Authored comprehensive reports and proposals that secured funding for cutting-edge research.

🛠️Tasks Completed as a Researcher:

Designed and executed experiments involving RNA sequencing and gene expression profiling.
Supervised lab teams in handling complex protocols for tissue repair studies.
Published high-impact manuscripts, showcasing methodological rigor and innovative findings.

🎤Oral Presentations:

Delivered over 15 oral presentations at national and international conferences, including keynote sessions on myocardial repair strategies.
Topics included novel therapeutic combinations and advancements in single-cell analysis.

🌟Success Factors:

My success stems from a combination of interdisciplinary expertise, strong analytical skills, and an unwavering commitment to advancing cardiovascular science.
Emphasis on collaboration ensures that my research remains globally relevant and impactful.

🌍Conclusion: 

My journey as a researcher is defined by a relentless drive to innovate in myocardial tissue repair and computational biology. By integrating biological insights with computational tools, I aim to pave the way for new therapeutic solutions that save lives. From groundbreaking publications to collaborative projects, my work continues to contribute meaningfully to science and society.

Top Notable Publications:

Article: Hypoxia adaptation mechanism in rats’ peripheral auditory system in high altitude migration: a time series transcriptome analysis
Authors: Wang, L., Yi, X., Zhou, Y., Su, X., Wang, P.
Year: 2024
Journal: Scientific Reports
Citations: 0

Letter: Individualized dynamic frailty-tailored therapy (DynaFiT) in elderly patients with newly diagnosed multiple myeloma: a prospective study
Authors: Zhang, Y., Liang, X., Xu, W., Dai, Y., Jin, F.
Year: 2024
Journal: Journal of Hematology and Oncology
Citations: 1

Article: Dynamics of minimal residual disease and its clinical implications in multiple myeloma: A retrospective real-life analysis
Authors: Xu, W., Liang, X., Liu, S., Dai, Y., Jin, F.
Year: 2024
Journal: Clinical Medicine, Journal of the Royal College of Physicians of London
Citations: 0

Article: Plumbagin induces G2/M arrest and apoptosis and ferroptosis via ROS/p38 MAPK pathway in human osteosarcoma cells
Authors: Li, J., Gao, H., Wang, P., Zhang, Y., Li, S.
Year: 2024
Journal: Alexandria Engineering Journal
Citations: 1

Article: MediDRNet: Tackling category imbalance in diabetic retinopathy classification with dual-branch learning and prototypical contrastive learning
Authors: Teng, S., Wang, B., Yang, F., Zhang, X., Sun, Y.
Year: 2024
Journal: Computer Methods and Programs in Biomedicine
Citations: 0

Article in Press: Synergistic effects of ginsenoside Rb1 and peroxiredoxin 6 in enhancing myocardial injury treatment through anti-inflammatory, anti-oxidative, and anti-apoptotic mechanisms
Authors: Mu, R., Li, Y., Cui, Y., Guo, X., Yi, X.
Year: 2024
Journal: Journal of Ginseng Research
Citations: 0

Letter: More than 2% circulating plasma cells as a prognostic biomarker in a large cohort of patients with newly-diagnosed multiple myeloma
Authors: Tian, M., Liang, X., Xu, W., Dai, Y., Jin, F.
Year: 2023
Journal: Annals of Hematology
Citations: 0

Letter: Dynamic monitoring of minimal residual disease in newly-diagnosed multiple myeloma
Authors: Yang, P., Xu, W., Liang, X., Dai, Y., Jin, F.
Year: 2023
Journal: American Journal of Hematology
Citations: 3

Article: Proposed risk-scoring model for estimating the prognostic impact of 1q gain in patients with newly diagnosed multiple myeloma
Authors: Yang, P., Chen, H., Liang, X., Dai, Y., Jin, F.
Year: 2023
Journal: American Journal of Hematology
Citations: 7

Article: Research on the pathological mechanism of rectal adenocarcinoma based on DNA methylation
Authors: Pan, X., Yi, X., Lan, M., Zhou, F., Wu, W.
Year: 2023
Journal: Medicine (United States)
Citations: 2

 

Paweł Rajewski | Cardiovascular risk | Best Research Article Award | Best Research Article Award

🏥Current Position and Roles:

Dr. Paweł Rajewski is a distinguished medical doctor, professor, and the rector of the Faculty of Health Sciences at the University of Health Sciences in Bydgoszcz. He holds the vital role of Provincial Consultant in Infectious Diseases for the Kuyavian-Pomeranian Voivodeship, providing oversight and strategic insights on infectious disease management in the region. Dr. Rajewski serves as the Head of the Department of Internal Medicine and Infectious Diseases at the Tadeusz Browicz Provincial Infectious Disease Hospital in Bydgoszcz, as well as the Head of the Liver, Internal, Infectious, and Metabolic Disorders Clinic at CM Gizińscy in Bydgoszcz. Previously, he served as the Medical Director and Head of the Department of Internal Medicine and Hepatology at the Emil Warmiński Multispecialist City Hospital. Through these roles, he contributes to the health of countless patients while also shaping medical policy and practice.

🎓Academic Background:

Dr. Rajewski’s academic journey has been marked by an enduring commitment to medicine, specializing in areas such as internal medicine, infectious diseases, hepatology, and clinical transplantation. His qualifications in these areas form the bedrock of his clinical and academic expertise, enabling him to deliver high-impact research and patient care in fields that are central to public health. Dr. Rajewski’s education includes specialty certifications as a lipidologist, accredited by the Polish Lipid Association, and an obesitologist with certifications from the Polish Association for the Study of Obesity and the Polish Society for Obesity Treatment.

📚Research Interests and Publication Achievements: 

Dr. Rajewski has contributed over 200 articles, primarily focused on metabolic disorders, obesity, liver diseases, and cardiovascular risk factors. His work, published in reputed medical journals, has been instrumental in advancing knowledge on these critical health issues. His research sheds light on complex metabolic processes, influencing both preventive and therapeutic approaches to conditions like non-alcoholic fatty liver disease and atherosclerosis. His publications are widely recognized for their scientific rigor and relevance, contributing to his esteemed reputation in the medical research community.

🔬Ongoing Research Projects:

Dr. Rajewski is currently engaged in various research projects that address emerging concerns in metabolic health and infectious diseases. His work on liver disease mechanisms and cardiovascular risk factors associated with obesity and metabolic syndrome aims to uncover better diagnostic markers and treatment pathways. A recent focus involves studying COVID-19’s impact on liver function and the interplay between viral infections and metabolic health, topics highly relevant in today’s healthcare landscape.

👥Professional Associations and Certifications: 

Dr. Rajewski’s memberships in prestigious medical associations, including the Polish Lipid Association and the Polish Association for the Study of Obesity, underscore his dedication to staying at the forefront of medical science. His certified expertise as a lipidologist and obesitologist enables him to approach health issues with a comprehensive understanding of lipid and metabolic disorders, enhancing the efficacy of treatments and preventive measures.

🏆Scholarships and Awards: 

Dr. Rajewski’s contributions to medicine have earned him numerous accolades, recognizing his achievements in research and clinical practice. These awards celebrate his innovation in metabolic research and his pivotal role in infectious disease management. His scholarship funding reflects a legacy of excellence and a commitment to advancing medical science.

📖Training & Workshops Attended:

In his pursuit of continual growth, Dr. Rajewski has attended a series of specialized workshops on bioinformatics, advanced diagnostics, and clinical applications in infectious disease management. These workshops equip him with cutting-edge skills that he applies to his daily work, benefiting patients and enhancing the training of his medical students.

💻Contributions to Bioinformatics and Clinical Research: 

A proficient bioinformatician, Dr. Rajewski integrates data science and computational tools in his research on metabolic diseases and infectious pathogens. By utilizing bioinformatics, he has been able to analyze complex datasets, leading to insights into genetic predispositions and disease progression. His ability to harness bioinformatics tools strengthens his work in both metabolic and infectious disease studies, positioning him at the cutting edge of medical research.

🎤Oral Presentations and Conferences: 

As a frequent presenter at national and international conferences, Dr. Rajewski shares his research findings with the medical community. His presentations cover topics like liver disease pathogenesis, metabolic syndrome treatments, and emerging infectious diseases. He contributes actively to knowledge exchange, with his lectures serving as valuable learning resources for both peers and students.

📊Key Tasks and Responsibilities as a Researcher:

In his research role, Dr. Rajewski coordinates multi-disciplinary teams, designing studies, and conducting extensive data analyses. His responsibilities include overseeing clinical trials and ensuring the ethical integrity of research protocols. His dedication to stringent research standards has led to significant findings that improve patient care protocols and inform public health strategies.

🌠Success Factors:

Dr. Rajewski attributes his success to his commitment to continuous learning, innovation, and collaboration. His ability to bridge theoretical research with practical applications in healthcare makes his contributions exceptionally valuable. Additionally, his leadership in the clinical setting exemplifies his holistic approach to healthcare, balancing research with direct patient care.

🔍Publications & Laboratory Experience:

Dr. Rajewski’s extensive laboratory experience includes advanced diagnostics in liver diseases, where he employs innovative techniques to diagnose and manage conditions like hepatitis and liver fibrosis. His publications detail his findings on the effectiveness of new biomarkers, offering insights that enhance both diagnostics and treatment options for liver and metabolic disorders.

🌐Conclusion: 

Dr. Paweł Rajewski’s career exemplifies a dedication to excellence in medicine, research, and public health. His multifaceted expertise in internal medicine, infectious diseases, and metabolic health has propelled him to the forefront of healthcare in Poland. Dr. Rajewski’s contributions are invaluable to the fields of hepatology and infectious disease, positively impacting patient care and advancing medical knowledge. Through his foundation, research, and clinical roles, he continues to shape the future of health sciences, creating a lasting legacy of compassion, knowledge, and innovation.

 

Top Notable Publications:

 

Hepatitis C Infection Is Not a Cardiovascular Risk Factor in Young Adults

Authors: Not listed; need to check for full author details.

Year: 2024

Citation: Biomedicines, 2024, 12(10), article 2400. DOI: 10.3390/biomedicines12102400.

Feasibility and Cardiometabolic Effects of Time-Restricted Eating in Patients with Metabolic Syndrome

Authors: Not listed; need to check for full author details.

Year: 2024

Citation: Nutrients, 2024, 16(12), article 1802. DOI: 10.3390/nu16121802.

Hepatitis C Infection as a Risk Factor for Hypertension and Cardiovascular Diseases: An EpiTer Multicenter Study

Authors: Not listed; need to check for full author details.

Year: 2022

Citation: Journal of Clinical Medicine, 2022, 11(17), article 5193. DOI: 10.3390/jcm11175193.

The Dynamics of Changes in the Concentration of IgG against the S1 Subunit in Polish Healthcare Workers in the Period from 1 to 12 Months after Injection, Including Four COVID-19 Vaccines

Authors: Not listed; need to check for full author details.

Year: 2022

Citation: Vaccines, 2022, 10(4), article 506. DOI: 10.3390/vaccines10040506.

HCV Genotype Has No Influence on the Incidence of Diabetes—EpiTer Multicentre Study

Authors: Not listed; need to check for full author details.

Year: 2022

Citation: Journal of Clinical Medicine, 2022, 11(2), article 379. DOI: 10.3390/jcm11020379.

Anti-SARS-CoV-2 IgG against the S Protein: A Comparison of BNT162b2, mRNA-1273, ChAdOx1 nCoV-2019 and Ad26.COV2.S Vaccines

Authors: Not listed; need to check for full author details.

Year: 2022

Citation: Vaccines, 2022, 10(1), article 99. DOI: 10.3390/vaccines10010099.

Pilot Clinical Trial of Time-Restricted Eating in Patients with Metabolic Syndrome

Authors: Not listed; need to check for full author details.

Year: 2021

Citation: Nutrients, 2021, 13(2), article 346. DOI: 10.3390/nu13020346.

Resveratrol’s Impact on Vascular Smooth Muscle Cells Hyporeactivity: The Role of Rho-Kinase Inhibition

Authors: Not listed; need to check for full author details.

Year: 2020

Citation: BioMed Research International, 2020, article 9012071. DOI: 10.1155/2020/9012071.

Zakażenie wirusem cytomegalii w praktyce klinicznej – diagnostyka, objawy i leczenie w świetle aktualnej wiedzy

Authors: Not listed; need to check for full author details.

Year: 2019

Citation: Forum Zakażeń, 2019, issue 4, article FZ2019042. DOI: 10.15374/FZ2019042.

Melatonin Supplementation Lowers Oxidative Stress and Regulates Adipokines in Obese Patients on a Calorie‐Restricted Diet

Authors: Not listed; need to check for full author details.

Year: 2017

Citation: Oxidative Medicine and Cellular Longevity, 2017, article 8494107. DOI: 10.1155/2017/8494107.

Stephane Manzo-Silberman | Cardiology | Best Researcher Award

Dr.Stephane Manzo-Silberman | Cardiology | Best Researcher Award 

 Dr. Stephane Manzo-Silberman, APHP Sorbonne University, France

Dr. Stephane Manzo-Silberman is a renowned cardiologist at Assistance Publique-Hôpitaux de Paris (APHP) and a faculty member at Sorbonne University, France. She specializes in cardiovascular diseases, with a focus on coronary artery disease and interventions. Dr. Manzo-Silberman is actively involved in clinical research, particularly in the fields of interventional cardiology and thrombosis, and she has contributed extensively to academic publications in these areas. In addition to her clinical work, she plays a key role in advancing medical education and promoting innovative cardiovascular therapies.

Profile:

Scopus Profile 

 

Education Qualification:

Dr. Stéphane Manzo-Silberman, MD, MSc, completed her medical and clinical training in cardiology at René Descartes University, Paris, where she earned her Doctorate in Medical Sciences (2005) and specialized in cardiology. She also holds a Master’s degree in Biological Sciences (2004). Her clinical expertise was further developed during her residency in internal medicine and cardiology (2000-2005), followed by advanced training as a senior resident in interventional cardiology at Cochin Hospital (2006-2011) and in coronary angiography and angioplasty at Clinique Pasteur, Toulouse (2006), under the mentorship of Pr. J Marco and Dr. J Fajadet.

Current Position:

Dr. Stéphane Manzo-Silberman currently serves as Senior Consultant at the Cardiac Catheterization Laboratory and Coronary Care Unit of the Cardiology Institute at Pitié-Salpêtrière Hospital, APHP, Sorbonne University, Paris. In this role, she specializes in interventional cardiology, managing complex cardiac procedures and providing advanced care for patients with coronary artery disease. Her position reflects her expertise in cardiovascular interventions and her dedication to improving clinical outcomes in cardiology.

Awards:

Dr. Stéphane Manzo-Silberman has received several prestigious awards throughout her career, including the French Society of Cardiology Prize for the best doctorate dissertation (2005) and the French Society of Angeology Junior Prize for the best master’s dissertation (2005). She was also honored with the Young Investigator Prize at JESFC 2017 and received an ESC Grant in 2020 to attend the Women Transforming Leadership Programme, highlighting her continued excellence in cardiology and leadership development.

Research Experience:

Dr. Stéphane Manzo-Silberman serves as the principal investigator in numerous multicenter academic clinical research studies. Her work includes leading pivotal studies such as the DOLORES registry, the DeFSSICA survey on acute heart failure management, and the First French Metaregistry on gender differences in myocardial infarction. She has also co-authored the EAPCI Women’s Survey on radiation protection in catheterization labs and chaired an EAPCI position statement on radiation protection during pregnancy for healthcare professionals. Additionally, she oversees major national projects like the WAMIF study on acute myocardial infarction in young women and the ACFA study on atrial fibrillation care pathways. Dr. Manzo-Silberman also actively directs theses and dissertations, mentoring the next generation of cardiology professionals.

Conclusion:

Dr. Stéphane Manzo-Silberman stands as a prominent figure in the field of cardiology, reflecting a deep commitment to advancing cardiovascular health and understanding. His extensive research, focused on the intricate dynamics of heart disease, particularly among diverse populations, underscores the critical importance of tailored medical approaches. Through his leadership in various studies and initiatives, Dr. Manzo-Silberman not only contributes to the scientific community but also advocates for improved patient outcomes and health equity. As he continues to explore new frontiers in cardiology, his work promises to inspire future generations of medical professionals and researchers, paving the way for innovative solutions to the challenges faced in cardiovascular care.

Top Notable Publications:

Laghlam, D., Benghanem, S., Ortuno, S., Hamzaoui, O., & Aissaoui, N. (2024). Management of cardiogenic shock: A narrative review. Annals of Intensive Care, 14(1), 45.

Sabouret, P., Barbato, E., Montalescot, G., Biondi-Zoccai, G., & Manzo-Silberman, S. (2024). Remembering our friend Jean-Philippe Collet: A giant in cardiology, a gentleman in life. Minerva Cardiology and Angiology, 72(4), 329-331.

Manzo-Silberman, S., Martin, A.-C., Boissier, F., Puymirat, E., & Delmas, C. (2024). Sex disparities in cardiogenic shock: Insights from the FRENSHOCK registry. Journal of Critical Care, 82, 154785.

Manzo-Silberman, S., Guedeney, P., Cayla, G., Montalescot, G., & Silvain, J. (2024). Ticagrelor vs Clopidogrel in Clopidogrel-Naive Patients with Chronic Coronary Syndrome. JACC: Cardiovascular Interventions, 17(12), 1413-1421.

Manzo-Silberman, S., Montalescot, G., & Lebreton, G. (2024). Has DanGer-Shock reshuffled the cards for mechanical circulatory support trials? Archives of Cardiovascular Diseases (Article in Press).

Hebbo, E., Khan, S., Manzo-Silberman, S., & Alasnag, M. (2024). The Clinical Approach to Angina in Women. Interventional Cardiology Clinics (Article in Press).

Manzo-Silberman, S., & Montalescot, G. (2023). Benefits of an observatory for myocardial infarction in women under 50: The WAMIF study. Annales de Cardiologie et d’Angeiologie, 72(6), 101691.

Manzo-Silberman, S., Chouihed, T., Ticelli, L.F., Roubille, F., & El Khoury, C. (2023). Assessment of atrial fibrillation in European emergency departments: Insights from a prospective observational multicenter study. Minerva Cardiology and Angiology, 74(4), 444-455.

Weizman, O., Tea, V., Marijon, E., Simon, T., & Danchin, N. (2023). Very long-term outcomes after acute myocardial infarction in young men and women: Insights from the FAST-MI program. Archives of Cardiovascular Diseases, 116(6-7), 324-334.

Sabouret, P., Manzo-Silberman, S., Alasnag, M., Biondi-Zoccai, G., & Bhatt, D.L. (2023). New approaches to reduce recurrent PCI: To angioplasty and beyond! European Heart Journal Open, 3(3), oead049.