The First Affiliated Hospital of Guangxi Medical University | China
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🫀DR. CHENLIANG GE, MD, PHD – A PIONEERING CARDIOVASCULAR RESEARCHER & CLINICIAN
Dr. Chenliang Ge is an accomplished physician-scientist whose work bridges clinical cardiology and data-driven medical research. With a robust foundation in both molecular mechanisms and large-scale epidemiological analysis, he continues to redefine the frontiers of cardiovascular science and patient care.
🎓 EARLY ACADEMIC PURSUITS
Dr. Ge began his academic journey with a Bachelor of Medicine, Bachelor of Surgery (MBBS) from Nanhua University, Hengyang (2008–2013). His passion for cardiology led him to pursue a Master of Science in Cardiology (2013–2016) from the same university. Advancing his specialization, he earned a PhD in Cardiology from Guangxi Medical University, Nanning, China (2019–2022), where he laid the groundwork for his breakthrough research in atrial fibrillation and molecular cardiology.
👨⚕️ PROFESSIONAL ENDEAVORS
Since 2016, Dr. Ge has served as an Attending Physician at the First Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi, China. In this role, he:
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Diagnoses and manages complex cardiovascular conditions.
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Specializes in radiofrequency ablation procedures for atrial fibrillation (AF) and supraventricular tachycardia.
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Combines clinical acumen with cutting-edge research to enhance patient outcomes.
🔬 CONTRIBUTIONS AND RESEARCH FOCUS ON CARDIO-ONCOLOGY
Dr. Ge’s research interests lie at the confluence of cardiology, artificial intelligence, and epidemiology. His contributions span three major domains:
1. EPIDEMIOLOGICAL INSIGHTS INTO CVD AND SYSTEMIC HEALTH
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Cardiovascular Disease and Cancer Mortality (2024): Identified heart failure as a standalone risk factor for cancer mortality using NHANES data.
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Physical Activity in Hypertension (2024): Demonstrated the life-extending benefits of moderate-intensity exercise in hypertensive patients.
2. MOLECULAR MECHANISMS IN ARRHYTHMIAS
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PhD Dissertation: Uncovered the role of TLR4 and NLRP3 inflammasome activation in atrial fibrillation.
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Key Finding (2022): TLR4 silencing reduced atrial fibrosis and AF susceptibility by downregulating NLRP3-TGF-β pathways, suggesting promising therapeutic targets.
3. TECHNOLOGY-DRIVEN DIAGNOSIS AND PROGNOSIS
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Echocardiographic Risk Stratification (2024): Developed an automated tool using echocardiography to predict left atrial low-voltage areas (LA-LVAs).
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Gene Signature for NIDCM Prognosis (2020): Created a two-gene model to predict survival and ventricular arrhythmias in non-ischemic dilated cardiomyopathy (NIDCM).
🧠 TECHNICAL AND CLINICAL EXPERTISE
RESEARCH SKILLS:
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Molecular biology techniques: PCR, Western blotting, immunohistochemistry.
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Confocal microscopy and in vivo/in vitro models.
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Epidemiological analysis using NHANES and UK Biobank datasets.
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Data analytics: Python, R, SPSS; Machine learning and deep learning.
CLINICAL EXPERTISE:
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Cardiac electrophysiology and ablation procedures.
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Echocardiography with tools like Philips Epic 7C and AutoStrain.
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Risk modeling and survival analysis for personalized cardiac care.
🌍 IMPACT AND INFLUENCE
Dr. Ge's work directly informs both clinical practice and public health policy. By connecting chronic diseases like heart failure and cancer, his findings push for integrated healthcare models. His gene-based and imaging-based diagnostic tools enable precision medicine, allowing for personalized and cost-effective interventions.
📚 ACADEMIC CITES
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Ge et al., 2020 – Gene Signature in NIDCM
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Ge et al., 2022 – TLR4 & NLRP3 in Atrial Fibrillation
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Ge et al., 2024 – Physical Activity in Hypertension & CVD-Cancer Link
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Chang et al., 2024 – Echocardiographic Risk Stratification (collaborative work)
🚀 LEGACY AND FUTURE CONTRIBUTIONS
With a unique blend of clinical insight and computational proficiency, Dr. Ge is at the forefront of next-generation cardiovascular care. His future directions likely include:
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Expanding the use of AI in cardiology diagnostics.
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Further investigating multi-system interactions in chronic diseases.
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Advocating for preventive cardiology through large-scale data and public health outreach.
His legacy is one of bridging bench-to-bedside translation, ensuring that rigorous research translates into better lives for patients globally.
📑 NOTABLE PUBLICATIONS
"The global burden of high BMI among adolescents between 1990 and 2021"
Authors: Ge C; Xiong J; Zhu R; Hong Z; Yan He
Journal: Communications medicine
Year: 2025
"Automatic Echocardiographic Assessment of Left Atrial Function for Prediction of Low-Voltage Areas in Non-Valvular Atrial Fibrillation"
Authors: Shuai Chang; Xiaofeng Zhang; Chenliang Ge; Yanfen Zhong; Decai Zeng; Yongzhi Cai; Tongtong
Journal: International Journal of General Medicine
Year: 2024
"Associations between cardiovascular diseases and cancer mortality: insights from a retrospective cohort analysis of NHANES data"
Authors: Ge C; Jiang Z; Long B; Lu Q; He Y
Journal: BMC public health
Year: 2024