Ikram Khan | Myocardial Infarction | Best Researcher Award

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Dr. Ikram Khan | Myocardial Infarction | Best Researcher Award

Dr. Ikram Khan, Lanzhou University, China

Dr. Ikram Khan is a postdoctoral researcher at Lanzhou University, China, specializing in genetics and microbiology. He earned his Ph.D. in Microbiology and is currently investigating the role of microbial diversity and metabolic pathways in acute myocardial infarction. His research explores the intricate relationships between blood, gut, and oral microbiomes in cardiovascular diseases. Dr. Khan previously completed his M.Phil. and Master’s in Genetics from Hazara University, Pakistan. With multiple research projects and international scholarships to his credit, he is committed to advancing precision medicine through microbiome-based diagnostics and therapeutic strategies in cardiovascular health.

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📘 EARLY ACADEMIC PURSUITS:

Dr. Ikram Khan began his academic journey in Genetics, earning his Master’s degree from Hazara University Mansehra, Pakistan (2012–2014) under the mentorship of Dr. Aziz-Ud-Uddin. He continued to pursue an M.Phil. in Genetics (2014–2017) at the same institution, where he conducted a pivotal study titled “Analysis of mitochondrial DNA mutation in patients with heart disease in Swat, Pakistan.” These formative years laid the groundwork for his passion in genetic and microbial underpinnings of cardiovascular diseases.

🧪 PROFESSIONAL ENDEAVORS:

Dr. Khan’s pursuit of scientific excellence led him to Lanzhou University, China, where he completed a Ph.D. in Microbiology (2018–2022). His doctoral research—“Characterization of circulating microbiome in patients with myocardial infarction at different stages”—was co-mentored by renowned scientists An Lizhi and Li Zhiqiang.

Currently, Dr. Khan is undertaking a Post-Doctorate (2023–2026) in Genetics at the same university, investigating how microbial diversity influences metabolic changes and functional disruptions in acute myocardial infarction. His research is mentored by Xie Xiaodong and Li Zhiqiang.

🔬 CONTRIBUTIONS AND RESEARCH FOCUS ON MYOCARDIAL INFARCTION:

Dr. Khan’s research lies at the intersection of microbiology, genetics, and cardiovascular medicine. His central aim is to unravel the complex dynamics between the blood, gut, and oral microbiomes and their metabolic byproducts, and how these elements collectively contribute to cardiovascular disease (CVD) progression.

His work is geared toward:

  • Identifying microbial biomarkers

  • Mapping metabolic pathways involved in myocardial infarction

  • Developing precision medicine strategies for early diagnosis and personalized treatment 💉

🏅 IMPACT AND INFLUENCE:

Dr. Khan’s research has:

  • Enhanced the understanding of microbiota-metabolome interplay in myocardial infarction

  • Offered novel diagnostic perspectives for cardiovascular and periodontal diseases

  • Set the stage for microbiome-based therapeutics and risk stratification tools in CVD

His projects include:

  • Profiling of blood, fecal, and salivary metabolomes

  • Comparative microbiota studies between healthy individuals and heart disease patients

  • Mitochondrial DNA mutation analysis as a potential genetic predisposition marker

🏆 HONORS AND AWARDS:

Chinese Government Scholarship for Ph.D. studies (2018–2022)
Prime Minister’s Fee Reimbursement Award for Outstanding Postgraduates (2016)
Prime Minister’s Laptop Award for Talented Students (2015)

📚 ACADEMIC CITES:

While still in the early stages of his postdoctoral research, Dr. Khan’s Ph.D. findings have already contributed to emerging literature on circulating microbiota and metabolomic profiling in cardiovascular settings. His work is expected to garner increased citations and collaborative interest from international microbiome and cardiology research circles.

🌍 LEGACY AND FUTURE CONTRIBUTIONS:

Dr. Ikram Khan is poised to become a leading voice in the microbiome-cardiovascular research nexus. His future work is expected to:

  • Uncover microbiota-based predictors of heart disease

  • Innovate non-invasive diagnostic tools based on metabolomic signatures

  • Contribute to global precision health initiatives

  • Inspire the next generation of geneticists and microbiome scientists in Pakistan and abroad

🌟CONCLUSION:

Dr. Ikram Khan stands out as a dedicated and forward-thinking researcher in the fields of genetics and microbiology, with a strong focus on cardiovascular health. His work bridges the gap between microbial communities and human disease, offering promising insights into precision medicine. By exploring how the blood, gut, and oral microbiomes influence metabolic functions and disease progression, Dr. Khan is contributing to the future of non-invasive diagnostics and targeted treatments. His academic journey and research achievements reflect a deep commitment to scientific innovation, and his work holds great potential for impactful advancements in global healthcare.

TOP NOTABLE PUBLICATIONS

Long-term exposure to high-concentration silver nanoparticles induced toxicity, fatality, bioaccumulation, and histological alteration in fish (Cyprinus carpio)
Authors: MA Kakakhel, F Wu, W Sajjad, Q Zhang, I Khan, K Ullah, W Wang
Journal: Environmental Sciences Europe
Year: 2021

Exploring blood microbial communities and their influence on human cardiovascular disease
Authors: I Khan, I Khan, Z Jianye, Z Xiaohua, M Khan, MG Hilal, MA Kakakhel, …
Journal: Journal of Clinical Laboratory Analysis
Year: 2022

Comparison of microbial populations in the blood of patients with myocardial infarction and healthy individuals
Authors: I Khan, I Khan, MA Kakakhel, Z Xiaowei, M Ting, I Ali, Y Fei, Z Jianye, …
Journal: Frontiers in Microbiology
Year: 2022

Analysis of the blood bacterial composition of patients with acute coronary syndrome and chronic coronary syndrome
Authors: I Khan, I Khan, M Usman, Z Jianye, ZX Wei, X Ping, L Zhiqiang, A Lizhe
Journal: Frontiers in Cellular and Infection Microbiology
Year: 2022

Circulating microbiota and metabolites: Insights into cardiovascular diseases
Authors: I Khan, I Khan, M Usman, Z Xiao Wei, X Ping, S Khan, F Khan, Z Jianye, …
Journal: Journal of Clinical Laboratory Analysis
Year: 2022

Gut microbiome as a treatment in colorectal cancer
Authors: AMYW Murad Khan, Suleman Shah, Wahid Shah, Ikram Khan, Hamid Ali, Ijaz Ali, …
Journal: International Reviews of Immunology
Year: 2024

The burden of omicron variant in Pakistan: an updated review
Authors: S Khan, SH Khan, F Haider, J Malik, F Khan, I Khan, I Ullah, MA Zia, …
Journal: COVID
Year: 2022

Genetic polymorphism within the wild population of Rhynchosia himalensis Benth. ex Baker
Authors: MKU Khan, N Muhammad, N Uddin, N Ali, I Khan, R Ullah
Journal: International Journal of Biosciences
Year: 2019

Assessing oral and toothbrush microbial profiles among high-altitude individuals with and without periodontal disease: a case-control study
Authors: S Lei, I Khan, X Zhang, T Chen, X Xie, X Zheng, Z Jianye, Z Li
Journal: BMC Oral Health
Year: 2024

Insights into the blood, gut, and oral microbiomes in Chinese patients with myocardial infarction: a case-control study
Authors: I Khan, I Khan, P Xie, Y Xiaohui, S Lei, T Song, Z Li, X Xie
Journal: BMC Microbiology
Year: 2025

Zhihui Zhang | Cardiovascular Research | Best Researcher Award

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Prof. Zhihui Zhang | Cardiovascular Research | Best Researcher Award

Prof. Zhihui Zhang, Army Medical University, China

Prof. Zhihui Zhang is a distinguished researcher at Army Medical University, China, specializing in cardiovascular diseases and stem cell therapy. His work focuses on endothelial seed cells, myocardial infarction, and immunosuppressive capabilities of mesenchymal stem cell-derived extracellular vesicles. He has published extensively in leading journals such as Genes and Diseases, Science Bulletin, and Stem Cell Research and Therapy. Prof. Zhang’s research contributes to advancing early diagnosis and targeted interventions for coronary microvascular dysfunction. His expertise in molecular biology and regenerative medicine has made significant impacts in cardiovascular research and clinical applications.

AUTHOR PROFILE

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🎓EARLY ACADEMIC PURSUITS:

Prof. Zhihui Zhang embarked on his academic journey with a deep passion for cardiovascular medicine. His early education laid a strong foundation in medical sciences, leading him to specialize in cardiology. His dedication and excellence in research and clinical practice positioned him for advanced studies and significant contributions to the field.

🏥PROFESSIONAL ENDEAVORS:

Dr. Zhang is the Director of the Department of Cardiology at the First Affiliated Hospital (Southwest Hospital) of the Army Medical University in Chongqing. His leadership extends beyond the hospital as he holds multiple prestigious roles:

  • Member of the Great Vessel Group under the Cardiology Branch of the Chinese Medical Association
  • Member of the Cardiologists’ Association of the Chinese Medical Doctor Association
  • Deputy Director of the Committee for Structural Heart Disease under the China Human Health Promotion Association
  • Deputy Director of the Cardiology Branch of the Chongqing Medical Association, leading the Interventional Cardiology and Imaging Group

🔬CONTRIBUTIONS AND RESEARCH FOCUS ON CARDIOVASCULAR RESEARCH:

Dr. Zhang is renowned for his expertise in interventional treatment of coronary heart disease and structural heart disease. His research focuses on:

  • Precise diagnosis and treatment of coronary heart disease
  • Interventional therapy for valvular heart diseases
  • Establishing a cohort for precise classification of myocardial ischemia
  • Creating a biobank and an artificial intelligence center for coronary angiography physiological assessment

Additionally, he has developed the professional Circa Met DB database, specializing in metabolic circadian rhythms.

🌍IMPACT AND INFLUENCE:

Dr. Zhang’s contributions have earned him numerous accolades, including:
🏆 Two first prizes for scientific progress in Chongqing
🏆 One first prize for scientific progress in Hubei Province
🏆 One second prize for military medical achievements

He has successfully led over 20 research projects, ranging from national natural science funds to key military and Chongqing talent programs. His pioneering work in cardiology has influenced national and military healthcare policies.

📖ACADEMIC CITATIONS:

Dr. Zhang has an outstanding publication record, with more than 30 SCI papers as the first or corresponding author (including co-first/co-corresponding). His research has been featured in top-tier journals such as:
📌 The Lancet
📌 Nature Metabolism
📌 Nature Communications
📌 Trends in Cell Biology

Additionally, he has contributed to drafting and setting 12 expert consensus documents, served as a deputy editor for two monographs, and contributed to nine other books. His work extends to two national invention patents, further solidifying his impact in the field.

🚀LEGACY AND FUTURE CONTRIBUTIONS:

As a recipient of the Outstanding Youth Talent Fund in National Defense Bioscience, Dr. Zhang is recognized as a key innovator in cardiology. He has been honored as an Innovation Leading Talent by the Chongqing Talents Program and as a Science and Technology Talent by the Army.

His legacy will continue to shape the future of cardiovascular medicine through:
✅ Advanced research in interventional cardiology
✅ Expansion of AI-driven medical diagnostics
✅ Development of groundbreaking therapeutic techniques
✅ Mentorship and training of future cardiologists

🌟CONCLUSION:

Prof. Zhihui Zhang is a visionary leader in cardiology, blending clinical excellence, groundbreaking research, and technological innovation. His contributions have not only transformed patient care but also advanced global medical knowledge. His work will undoubtedly influence generations of medical professionals and redefine the future of cardiovascular treatment.

TOP NOTABLE PUBLICATIONS

Single nucleotide polymorphisms: Implications in the early diagnosis and targeted intervention of coronary microvascular dysfunction

Authors: Dingyuan Tian, Jie Li, Qingyuan Yang, Zhihui Zhang, Fang Deng

Journal: Genes and Diseases

Year: 2025

Circadian nutrition: is meal timing an elixir for fatigue?

Authors: Zhihui Zhang, Lu Yan, Jonas T. Treebak, Min-Dian Li

Journal: Science Bulletin

Year: 2025

Foxo1 drives the TGFβ1-dependent dichotomy of Th17 cell fates

Authors: Mengjuan Zhang, Yude Guan, Meijuan Han, Xiaomin Zhang, Song Zhang

Journal: Journal of Leukocyte Biology

Year: 2025

The short-term outcomes and risk factors of post-myocardial infarction ventricular septal rupture: a multi-center retrospective study

Authors: Wenjian Luo, Li Wen, Jinning Zhang, Zhexue Qin, Shiyong Yu

Journal: Journal of Cardiothoracic Surgery

Year: 2024

Sources and applications of endothelial seed cells: a review

Authors: Dan Deng, Yu Zhang, Bo Tang, Zhihui Zhang

Journal: Stem Cell Research and Therapy

Year: 2024

Enhanced immunosuppressive capability of mesenchymal stem cell-derived small extracellular vesicles with high expression of CD73 in experimental autoimmune uveitis

Authors: Yanan Duan, Xiteng Chen, Hui Shao, Jiawei Wang, Xiaomin Zhang

Journal: Stem Cell Research and Therapy

Year: 2024

Deciphering metabolic heterogeneity in retinoblastoma unravels the role of monocarboxylate transporter 1 in tumor progression

Authors: Junjie Tang, Yaoming Liu, Yinghao Wang, Ping Zhang, Rong Lu

Journal: Biomarker Research

Year: 2024

Associations between non-insulin-based insulin resistance indices and heart failure prevalence in overweight/obesity adults without diabetes mellitus: evidence from the NHANES 2001–2018

Authors: Diyu Cui, Chao Zhang, Yi Chen, Yu Zhang, Ping Zhu

Journal: Lipids in Health and Disease

Year: 2024

Single-cell transcriptomics enable the characterization of local extension in retinoblastoma

Authors: Yaoming Liu, Wei Hu, Yanjie Xie, Shengli Li, Rong Lu

Journal: Communications Biology

Year: 2024

Clinical characteristics of patients with moderate or severe valvular heart disease

Authors: Hao Gao, Yuzhu Lei, Haiyun Huang, Yanxiu Chen, Zhihui Zhang

Journal: Chinese Journal of Cardiology

Year: 2024