The Affiliated Hospital of Southwest Medical University | China
Author Profile:
Scopus
👨⚕️ MR. FENGXU YU – PIONEER IN CARDIOVASCULAR INNOVATION
🎓 EARLY ACADEMIC PURSUITS
Born in January 1976, Professor Fengxu Yu embarked on his medical journey with a strong academic foundation, earning his M.D. and later achieving qualifications as a doctoral supervisor. His passion for cardiovascular science led him to pursue postdoctoral training in France, equipping him with a global perspective and refined clinical research skills. This international exposure laid the groundwork for his future leadership in complex cardiovascular research and surgical practice.
💼 PROFESSIONAL ENDEAVORS
Currently serving as a Professor at The Affiliated Hospital of Southwest Medical University, Dr. Yu holds several distinguished roles:
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Standing Committee Member, Cardiac Surgery Committee (CAMEA)
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Committee Member, Heart Valve Committee (CRHA)
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Vice Chair, Sichuan Thoracic & Cardiac Surgery Association
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Academic Leader, recognized by the Sichuan Health Commission
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Member, Asian Heart Valve Society, China Chapter
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Recipient, Luzhou Top Talent Award
His consistent dedication has cemented his role as a leading figure in thoracic and cardiac surgery across China.
Dr. Yu’s research endeavors focus on molecular and biomechanical mechanisms in cardiovascular disease, especially atrial fibrillation (AF), atherosclerosis, and aortic dissection. His current areas of exploration include:
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Non-coding RNAs (e.g., circRNA/ceRNA networks) in AF pathogenesis
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Application of induced pluripotent stem cells in modeling AF
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Effects of shear stress on vascular endothelial health and its link to atherosclerosis
Through these efforts, Dr. Yu bridges basic science with clinical relevance, advancing the future of personalized medicine.
📊 IMPACT AND INFLUENCE
As a principal investigator, Dr. Yu has led nearly 20 major research projects funded by provincial and municipal institutions. He has also contributed to 30+ collaborative studies as a lead or co-investigator. His academic output includes over 50 peer-reviewed publications, with 12 articles indexed in SCI journals and 20+ papers in national core journals, showcasing his thought leadership in cardiovascular science.
📚 SELECTED RESEARCH PROJECTS
Some of Dr. Yu’s notable funded projects include:
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Mechanism of Shear Stress-Downregulated Annexin A1 (2019)
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circRNA-Regulated ceRNA Networks in AF (2025)
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Personalized Warfarin Therapy Post-Valve Replacement (2022)
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Hsa_circ_0025573—miR-133b—MMP9 in AF Pathogenesis (2022)
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SRB1-Mediated Endothelial Injury in Atherosclerosis (2018)
These projects reflect a multidisciplinary approach to understanding and treating cardiovascular conditions.
🏅 ACADEMIC CITES AND MEMBERSHIPS
Professor Yu actively contributes to national and international academic bodies. His memberships include:
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CAMEA – Cardiac Surgery Committee
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CRHA – Heart Valve Committee
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Sichuan Thoracic & Cardiac Surgery Association
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Asian Heart Valve Society – China Chapter
These affiliations enhance his visibility in shaping future cardiac surgery standards and innovations.
🌟 LEGACY AND FUTURE CONTRIBUTIONS
Professor Fengxu Yu is a mentor, innovator, and academic leader. His mentorship of graduate students, collaboration with international institutions such as Heidelberg University, and continued work on translational research ensure a legacy of impactful science. As cardiovascular disease remains a global challenge, his pioneering work in non-coding RNA and biomechanical interactions is poised to redefine prevention and treatment strategies.
📑 NOTABLE PUBLICATIONS
"Myocardial infarction serum preconditioning bone marrow mesenchymal stem cell-derived exosomes enhance anti-fibrosis in rat myocardial infarction hearts"
Authors: Y., Gan, Yang , C., Wang, Changyi , R., Liao, Ruili , ... H., Liu, Hui , Y., Fu, Yong
Journal: Molecular and Cellular Biochemistry.
Year: 2025
"Identification of the optimal reference genes for atrial fibrillation model established by iPSC-derived atrial myocytes"
Authors: L., Li, Lei , Z., Zhao, Zijuan , Z., Liu, Zihao , ... Y., Nie, Yongmei , F., Yu, Fengxu
Journal: BMC Genomics
Year: 2024
"Postoperative delirium prediction after cardiac surgery using machine learning models"
Authors: T., Yang, Tan , H., Yang, Hai , Y., Liu, Yan , ... Y., Zhang, Ying , F., Yu, Fengxu
Journal: Computers in Biology and Medicine
Year: 2024