Prof. Zhihui Zhang is a distinguished researcher at Army Medical University, China, specializing in cardiovascular diseases and stem cell therapy. His work focuses on endothelial seed cells, myocardial infarction, and immunosuppressive capabilities of mesenchymal stem cell-derived extracellular vesicles. He has published extensively in leading journals such as Genes and Diseases, Science Bulletin, and Stem Cell Research and Therapy. Prof. Zhang’s research contributes to advancing early diagnosis and targeted interventions for coronary microvascular dysfunction. His expertise in molecular biology and regenerative medicine has made significant impacts in cardiovascular research and clinical applications.
AUTHOR PROFILE
Scopus Profile
Orcid Profile
🎓EARLY ACADEMIC PURSUITS:
Prof. Zhihui Zhang embarked on his academic journey with a deep passion for cardiovascular medicine. His early education laid a strong foundation in medical sciences, leading him to specialize in cardiology. His dedication and excellence in research and clinical practice positioned him for advanced studies and significant contributions to the field.
🏥PROFESSIONAL ENDEAVORS:
Dr. Zhang is the Director of the Department of Cardiology at the First Affiliated Hospital (Southwest Hospital) of the Army Medical University in Chongqing. His leadership extends beyond the hospital as he holds multiple prestigious roles:
- Member of the Great Vessel Group under the Cardiology Branch of the Chinese Medical Association
- Member of the Cardiologists’ Association of the Chinese Medical Doctor Association
- Deputy Director of the Committee for Structural Heart Disease under the China Human Health Promotion Association
- Deputy Director of the Cardiology Branch of the Chongqing Medical Association, leading the Interventional Cardiology and Imaging Group
Dr. Zhang is renowned for his expertise in interventional treatment of coronary heart disease and structural heart disease. His research focuses on:
- Precise diagnosis and treatment of coronary heart disease
- Interventional therapy for valvular heart diseases
- Establishing a cohort for precise classification of myocardial ischemia
- Creating a biobank and an artificial intelligence center for coronary angiography physiological assessment
Additionally, he has developed the professional Circa Met DB database, specializing in metabolic circadian rhythms.
🌍IMPACT AND INFLUENCE:
Dr. Zhang’s contributions have earned him numerous accolades, including:
🏆 Two first prizes for scientific progress in Chongqing
🏆 One first prize for scientific progress in Hubei Province
🏆 One second prize for military medical achievements
He has successfully led over 20 research projects, ranging from national natural science funds to key military and Chongqing talent programs. His pioneering work in cardiology has influenced national and military healthcare policies.
📖ACADEMIC CITATIONS:
Dr. Zhang has an outstanding publication record, with more than 30 SCI papers as the first or corresponding author (including co-first/co-corresponding). His research has been featured in top-tier journals such as:
📌 The Lancet
📌 Nature Metabolism
📌 Nature Communications
📌 Trends in Cell Biology
Additionally, he has contributed to drafting and setting 12 expert consensus documents, served as a deputy editor for two monographs, and contributed to nine other books. His work extends to two national invention patents, further solidifying his impact in the field.
🚀LEGACY AND FUTURE CONTRIBUTIONS:
As a recipient of the Outstanding Youth Talent Fund in National Defense Bioscience, Dr. Zhang is recognized as a key innovator in cardiology. He has been honored as an Innovation Leading Talent by the Chongqing Talents Program and as a Science and Technology Talent by the Army.
His legacy will continue to shape the future of cardiovascular medicine through:
✅ Advanced research in interventional cardiology
✅ Expansion of AI-driven medical diagnostics
✅ Development of groundbreaking therapeutic techniques
✅ Mentorship and training of future cardiologists
🌟CONCLUSION:
Prof. Zhihui Zhang is a visionary leader in cardiology, blending clinical excellence, groundbreaking research, and technological innovation. His contributions have not only transformed patient care but also advanced global medical knowledge. His work will undoubtedly influence generations of medical professionals and redefine the future of cardiovascular treatment.
TOP NOTABLE PUBLICATIONS
Single nucleotide polymorphisms: Implications in the early diagnosis and targeted intervention of coronary microvascular dysfunction
Authors: Dingyuan Tian, Jie Li, Qingyuan Yang, Zhihui Zhang, Fang Deng
Journal: Genes and Diseases
Year: 2025
Circadian nutrition: is meal timing an elixir for fatigue?
Authors: Zhihui Zhang, Lu Yan, Jonas T. Treebak, Min-Dian Li
Journal: Science Bulletin
Year: 2025
Foxo1 drives the TGFβ1-dependent dichotomy of Th17 cell fates
Authors: Mengjuan Zhang, Yude Guan, Meijuan Han, Xiaomin Zhang, Song Zhang
Journal: Journal of Leukocyte Biology
Year: 2025
The short-term outcomes and risk factors of post-myocardial infarction ventricular septal rupture: a multi-center retrospective study
Authors: Wenjian Luo, Li Wen, Jinning Zhang, Zhexue Qin, Shiyong Yu
Journal: Journal of Cardiothoracic Surgery
Year: 2024
Sources and applications of endothelial seed cells: a review
Authors: Dan Deng, Yu Zhang, Bo Tang, Zhihui Zhang
Journal: Stem Cell Research and Therapy
Year: 2024
Enhanced immunosuppressive capability of mesenchymal stem cell-derived small extracellular vesicles with high expression of CD73 in experimental autoimmune uveitis
Authors: Yanan Duan, Xiteng Chen, Hui Shao, Jiawei Wang, Xiaomin Zhang
Journal: Stem Cell Research and Therapy
Year: 2024
Deciphering metabolic heterogeneity in retinoblastoma unravels the role of monocarboxylate transporter 1 in tumor progression
Authors: Junjie Tang, Yaoming Liu, Yinghao Wang, Ping Zhang, Rong Lu
Journal: Biomarker Research
Year: 2024
Associations between non-insulin-based insulin resistance indices and heart failure prevalence in overweight/obesity adults without diabetes mellitus: evidence from the NHANES 2001–2018
Authors: Diyu Cui, Chao Zhang, Yi Chen, Yu Zhang, Ping Zhu
Journal: Lipids in Health and Disease
Year: 2024
Single-cell transcriptomics enable the characterization of local extension in retinoblastoma
Authors: Yaoming Liu, Wei Hu, Yanjie Xie, Shengli Li, Rong Lu
Journal: Communications Biology
Year: 2024
Clinical characteristics of patients with moderate or severe valvular heart disease
Authors: Hao Gao, Yuzhu Lei, Haiyun Huang, Yanxiu Chen, Zhihui Zhang
Journal: Chinese Journal of Cardiology
Year: 2024