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Dr. Alessandra Granata : Vascular Dementia

professor at University of Cambridge, United Kingdom

Dr. Alessandra Granata is a distinguished figure in the field of clinical neurosciences, associated with the Heart & Lung Research Institute at the Cambridge Biomedical Campus, Cambridge, UK. Specializing in neurological research, Dr. Granata has made significant contributions to the understanding of disorders affecting the heart and lungs. Her work addresses critical aspects of clinical neurosciences, reflecting a commitment to advancing medical knowledge. With a focus on Papworth Road, Dr. Granata’s contributions at the intersection of neurology and cardiovascular health exemplify her dedication to improving patient outcomes. Her presence at the forefront of medical research marks her as a key contributor to advancements in clinical neurosciences.


Professional Profile


Dr. Alessandra Granata, a distinguished researcher, pursued a Ph.D. from 2000 to 2004 at the MRC Centre for Developmental Neurobiology, King’s College, London. Her groundbreaking work during this period advanced the understanding of developmental neurobiology. Prior to her doctoral studies, Dr. Granata earned a BSc Honours in Biology from the University of Milan, Italy, spanning 1993 to 1999. This foundational education laid the groundwork for her impactful contributions in the field. Dr. Granata’s academic journey reflects a commitment to excellence, positioning her as a key figure in developmental neurobiology, bridging insights from King’s College to her formative years in Milan.


Dr. Alessandra Granata, an esteemed researcher, serves on the Editorial Board for BMC Cardiovascular Disorders since 2021, showcasing her commitment to advancing cardiovascular research. A member of the International Society for Stem Cell Research (ISSCR) since 2018, Dr. Granata stays at the forefront of stem cell advancements. Her affiliations with the British Society for Cardiovascular Research since 2017 and the British Society for Cell Biology since 2004 underscore her enduring dedication to scientific communities. With a focus on cardiovascular disorders and stem cell research, Dr. Granata’s multifaceted involvement highlights her influential role in shaping advancements and fostering collaboration within these critical scientific domains.

work experience

Dr. Alessandra Granata is a distinguished researcher known for her impactful contributions to neuroscience. Currently an MRF Fellow for the Medical Research Foundation Stroke in Young Adults, she focuses on genetic forms of stroke and vascular dementia using human stem cell-based models. As a Senior Research Associate at the University of Cambridge, Dr. Granata leads a group dedicated to developing stem cell-derived models for genetic stroke and cerebral small vessel disease. Her prior roles include postdoctoral research at the Anne McLaren Laboratory, focusing on Marfan Syndrome, and investigating DYT1 Dystonia at the Royal Free & University College Medical School. Throughout her career, Dr. Granata’s work reflects a commitment to advancing our understanding of neurological disorders.

Publications top noted:

A novel human iPSC model of COL4A1/A2 small vessel disease unveils a key pathogenic role of matrix metalloproteinases

https://pubmed.ncbi.nlm.nih.gov/35733040/Functional genomics in stroke: current and future applications of iPSCs and gene editing to dissect the function of risk variants

A phenotypic screen of Marfan syndrome iPSC-derived vascular smooth muscle cells uncovers GSK3β as a new target

A multi-disciplinary commentary on preclinical research to investigate vascular contributions to dementia

The Histone Deacetylase 9 Stroke-Risk Variant Promotes Apoptosis and Inflammation in a Human iPSC-Derived Smooth Muscle Cells Model

Global proteomic analysis of extracellular matrix in mouse and human brain highlights relevance to cerebrovascular disease





Dr. Alessandra Granata | Vascular Dementia | Best Researcher Award

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