Yuriy Borshchev | Ischemic-reperfusion injury | Best Researcher Award

Dr. Yuriy Borshchev | Ischemic-reperfusion injury | Best Researcher Award

Almazov National Medical Research Center | Russia

Author Profile:

Scopus

Orcid

🏅 BEST RESEARCHER PROFILE: DR. YURIY BORSHCHEV

👨‍🎓 EARLY ACADEMIC PURSUITS

Dr. Yuriy Borshchev was born on April 13, 1968, in Chisinau, Republic of Moldova. His academic journey began at Chisinau State University, where he pursued his studies from 1985 to 1992 in the Faculty of Biology and Soil Science, majoring in Biology with a specialization in Human and Animal Physiology. This foundational education laid the groundwork for his future contributions to physiological and biomedical research.

💼 PROFESSIONAL ENDEAVORS

Before fully immersing himself in academia, Dr. Borshchev gained extensive practical experience in various industries. Between 1992 and 2007, he worked in mechanical engineering and food processing enterprises in Moldova, advancing from logistics roles to leadership positions such as enterprise director. In 2007, he transitioned into scientific research, joining the Pavlov Institute of Animal Physiology as a laboratory assistant and later as a research associate.

By 2012, he earned his PhD (Candidate of Biological Sciences) with a dissertation focused on the effects of probiotic bacteria on intestinal enzymes in rats with dysbiosis. His career progressed as he became a senior researcher at the Institute of Experimental Medicine and, later, the Almazov National Medical Research Center, where he now serves as Head of the Physiological Microendoecology Department.

🔬 CONTRIBUTIONS AND RESEARCH FOCUS ON ISCHEMIC-REPERFUSION INJURY

Dr. Borshchev's work sits at the intersection of cardiology, gastroenterology, microbiology, and pathophysiology. His key contributions include:

  • Development of novel experimental biomedical models for studying inflammation and metabolic disorders.

  • Creation of a systemic inflammatory response model in rats, used to evaluate the therapeutic potential of probiotic bacteria.

  • Pioneering research into the influence of intestinal microbiota on myocardial resistance to ischemia-reperfusion injury.

  • Broad expertise in biochemical, histological, microbiological, and behavioral methodologies, as well as surgical experimentation on lab animals.

🌍 IMPACT AND INFLUENCE

Dr. Borshchev has significantly contributed to experimental medicine through:

  • Over 70 scientific publications, including 40 in SCI/SCIE journals and 18 indexed in Scopus/Web of Science/PubMed.

  • An H-index of 5, with a citation count of 22, reflecting ongoing recognition in specialized fields.

  • 8 completed research projects and 2 ongoing, amounting to over $800,000 USD in funding.

  • 5 industry-sponsored consultancy projects, demonstrating applied research impact.

  • Author and contributor to 8 books and proceedings with ISBNs.

  • One patent published, highlighting innovation in translational medical science.

📚 ACADEMIC CITES AND LEADERSHIP

In his academic and professional capacity, Dr. Borshchev:

  • Has served in editorial and reviewer roles for 2 journals/conferences.

  • Delivered 4 invited talks, attended 15 conferences, and visited 4 countries for international collaboration.

  • Supervised and graduated 2 research scholars, and is actively involved in collaborative scientific projects.

  • Maintains active profiles in global databases:

    • Scopus Author ID: 57206730176

    • Web of Science Researcher ID: IDE-1363-2014

    • elibrary.ru SPIN-code: 3454-4113

🧪 LEGACY AND FUTURE CONTRIBUTIONS

As a leading scientist at the Almazov National Medical Research Center, Dr. Borshchev continues to push the boundaries of experimental and translational medicine. His legacy is built on:

  • Bridging microbial ecology and systemic physiology.

  • Advancing knowledge in cardio-gastrointestinal interactions.

  • Training the next generation of scientists and building collaborative international partnerships.

Looking forward, Dr. Borshchev aims to expand his department's work into oncopharmacology and metabolic disease modeling, with the potential to influence both clinical therapies and preclinical standards.

🏆 AWARDS AND PROFESSIONAL AFFILIATIONS

Dr. Borshchev has been honored with 4 research awards, and holds 2 professional body memberships. He is committed to ethical research, demonstrated by his GLP-certified training in preclinical study protocols and laboratory animal handling.

🤝 COLLABORATIONS AND NETWORKING

  • 2 active MoUs with universities/industries.

  • 2 joint collaborative publications/projects.

  • Contributed to scientific communities across Russia, Europe, and other research-focused regions.

📌 CONCLUSION

Dr. Yuriy Borshchev exemplifies the qualities of a Best Researcher Award recipient: innovative, dedicated, and globally engaged. His work stands out for its relevance, depth, and potential to influence medical science well into the future.

📑 NOTABLE PUBLICATIONS

"Brain-Derived Neurotrophic Factor Cancels the Cardioprotective Effect of Interleukin-2 in a Model of Systemic Inflammatory Response in Rats"

Authors: I.Y., Burovenko, Inessa Yu , Y.Y., Borshchev, Yury Yu , S.M., Minasyan, Svetlana M. , ... O.V., Borshcheva, Olga V. , M.M., Galagudza, Mikhail M.
Journal: Bulletin of Experimental Biology and Medicine
Year: 2025

"Changes in the activity of amylase, alkaline phosphatase and lipase in placenta and umbilical cord blood in women in labor with gestational diabetes mellitus"

Authors: Elena V. Kolodkina; Sergey A. Lytaev; Michael M. Galagudza; Alexander B. Loginov; Tatyana M. Pervunina; Stanislav I. Sitkin; Yuri Yu. Borschchev; Olga V. Borschcheva
Journal: Medical academic journal
Year: 2025

Rafaella Mendes Zambetta | Intracranial Compliance | Best Researcher Award

Mrs. Rafaella Mendes Zambetta | Intracranial Compliance | Best Researcher Award

Mrs. Rafaella Mendes Zambetta, Federal University of São Carlos, Brazil

Mrs. Rafaella Mendes Zambetta is a researcher and academic affiliated with the Federal University of São Carlos (UFSCar), Brazil. Her work focuses on areas related to education, research methodologies, and social sciences. Through her involvement at UFSCar, she contributes to interdisciplinary studies and projects that aim to improve educational practices and foster innovation within academic research.

Profile:

Scopus Profile 

Orcid Profile

 

Education:

Mrs. Rafaella Mendes Zambetta is a Ph.D. fellow in Physical Therapy at the Federal University of São Carlos (UFSCar), Brazil, focusing on neurological rehabilitation. Since 2019, her research has explored the effects of head-down tilt on intracranial pressure and cardiovascular autonomic modulation, with applications for space travel. She holds a specialization in Neurofunctional Physiotherapy (2021) and a B.A. in Physical Therapy (2018), both from UFSCar. Her work has included studies on stroke recovery and brain compliance. Mrs. Zambetta has also completed training in Constraint-Induced Movement Therapy, furthering her expertise in rehabilitation techniques.

Professional Experiences:

In 2018, Mrs. Rafaella Mendes Zambetta completed a comprehensive traineeship at the Federal University of São Carlos (UFSCar), Brazil, where she gained hands-on experience in various areas of physical therapy. These included Neurofunctional, Geriatric, Rheumatology, Orthopedic, Cardiorespiratory, Basic Care, Neuropediatric, and Hospital-based Physical Therapy. Her diverse training allowed her to develop a broad skill set in patient care across different specialties, enhancing her expertise in rehabilitation and therapy.

Research Experiences:

Mrs. Rafaella Mendes Zambetta is a Ph.D. Fellow in Physical Therapy at the Neurological Physical Therapy Laboratory (LaFiN), Federal University of São Carlos, Brazil, where she has been working since 2019 under the supervision of Prof. Thiago Luiz de Russo. She is currently a Visiting Fellow at both the Gordon Center for Medical Imaging at Massachusetts General Hospital and the Berenson-Allen Center for Noninvasive Brain Stimulation at Beth Israel Deaconess Medical Center in Boston, under the guidance of Prof. Emiliano Santarnecchi (Aug 2023 – Jul 2024). Her work focuses on neuroscience and neuromodulation.

Top Notable Publications:

Article:
Title: Is the ICP pulse waveform P2/P1 ratio during -6° head-down tilt associated with relative VO2 peak? A non-invasive intracranial compliance monitoring approach
Authors: Mendes Zambetta, R., Signini, É.D.F., Catai, A.M., Frigieri, G., Russo, T.L.
Journal: Brain and Spine
Year: 2024
Citations: 0

Review:
Title: Effects of weightlessness on the cardiovascular system: a systematic review and meta-analysis
Authors: Mendes Zambetta, R., Signini, É.D.F., Ocamoto, G.N., Santarnecchi, E., Russo, T.L.
Journal: Frontiers in Physiology
Year: 2024
Citations: 0

Review:
Title: Intracranial Compliance Concepts and Assessment: A Scoping Review
Authors: Ocamoto, G.N., Russo, T.L., Mendes Zambetta, R., Rabelo, N.N., Spavieri Júnior, D.L.
Journal: Frontiers in Neurology
Year: 2021
Citations: 25

Article:
Title: Compensatory neuromuscular junction adaptations of forelimb muscles in focal cortical ischemia in rats
Authors: Estrada-Bonilla, Y.C., Castro de Souza-Tomé, P.A., Faturi, F.M., Jones, T.A., Russo, T.L.
Journal: Brain and Behavior
Year: 2020
Citations: 3

Dr. Alessandra Granata | Vascular Dementia | Best Researcher Award

Dr. Alessandra Granata : Vascular Dementia

professor at University of Cambridge, United Kingdom

Dr. Alessandra Granata is a distinguished figure in the field of clinical neurosciences, associated with the Heart & Lung Research Institute at the Cambridge Biomedical Campus, Cambridge, UK. Specializing in neurological research, Dr. Granata has made significant contributions to the understanding of disorders affecting the heart and lungs. Her work addresses critical aspects of clinical neurosciences, reflecting a commitment to advancing medical knowledge. With a focus on Papworth Road, Dr. Granata’s contributions at the intersection of neurology and cardiovascular health exemplify her dedication to improving patient outcomes. Her presence at the forefront of medical research marks her as a key contributor to advancements in clinical neurosciences.

 

Professional Profile

Education:

Dr. Alessandra Granata, a distinguished researcher, pursued a Ph.D. from 2000 to 2004 at the MRC Centre for Developmental Neurobiology, King’s College, London. Her groundbreaking work during this period advanced the understanding of developmental neurobiology. Prior to her doctoral studies, Dr. Granata earned a BSc Honours in Biology from the University of Milan, Italy, spanning 1993 to 1999. This foundational education laid the groundwork for her impactful contributions in the field. Dr. Granata’s academic journey reflects a commitment to excellence, positioning her as a key figure in developmental neurobiology, bridging insights from King’s College to her formative years in Milan.

Membership

Dr. Alessandra Granata, an esteemed researcher, serves on the Editorial Board for BMC Cardiovascular Disorders since 2021, showcasing her commitment to advancing cardiovascular research. A member of the International Society for Stem Cell Research (ISSCR) since 2018, Dr. Granata stays at the forefront of stem cell advancements. Her affiliations with the British Society for Cardiovascular Research since 2017 and the British Society for Cell Biology since 2004 underscore her enduring dedication to scientific communities. With a focus on cardiovascular disorders and stem cell research, Dr. Granata’s multifaceted involvement highlights her influential role in shaping advancements and fostering collaboration within these critical scientific domains.

work experience

Dr. Alessandra Granata is a distinguished researcher known for her impactful contributions to neuroscience. Currently an MRF Fellow for the Medical Research Foundation Stroke in Young Adults, she focuses on genetic forms of stroke and vascular dementia using human stem cell-based models. As a Senior Research Associate at the University of Cambridge, Dr. Granata leads a group dedicated to developing stem cell-derived models for genetic stroke and cerebral small vessel disease. Her prior roles include postdoctoral research at the Anne McLaren Laboratory, focusing on Marfan Syndrome, and investigating DYT1 Dystonia at the Royal Free & University College Medical School. Throughout her career, Dr. Granata’s work reflects a commitment to advancing our understanding of neurological disorders.

Publications top noted:

A novel human iPSC model of COL4A1/A2 small vessel disease unveils a key pathogenic role of matrix metalloproteinases

https://pubmed.ncbi.nlm.nih.gov/35733040/Functional genomics in stroke: current and future applications of iPSCs and gene editing to dissect the function of risk variants

A phenotypic screen of Marfan syndrome iPSC-derived vascular smooth muscle cells uncovers GSK3β as a new target

A multi-disciplinary commentary on preclinical research to investigate vascular contributions to dementia

The Histone Deacetylase 9 Stroke-Risk Variant Promotes Apoptosis and Inflammation in a Human iPSC-Derived Smooth Muscle Cells Model

Global proteomic analysis of extracellular matrix in mouse and human brain highlights relevance to cerebrovascular disease