Yan Shi | Congenital Heart Defects | Best Researcher Award

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Dr. Yan Shi | Congenital Heart Defects | Best Researcher Award

Guangdong Provincial People's Hospital | China

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🌟 DR. YAN SHI: PIONEERING GENETICS RESEARCHER IN CARDIOVASCULAR DEVELOPMENT 🧬❤️

🎓 EARLY ACADEMIC PURSUITS

Yan Shi , a dedicated scientist from China, embarked on her academic journey in the field of life sciences with an undergraduate degree in Biological Engineering from Shenyang University (2008-2012). She continued to follow her passion for genetics at Hunan Normal University, earning a Master’s Degree in Genetics (2012-2014), and later completed her Ph.D. in Genetics in 2019. Throughout her studies, she developed a strong foundation in molecular biology, focusing on the genetic mechanisms underlying human diseases.

🏥 PROFESSIONAL ENDEAVORS

After obtaining her Ph.D., Dr. Yan Shi advanced her career through postdoctoral research at the Department of Pediatric Cardiac Surgery, Guangdong Provincial People's Hospital (2019-2024). In July 2024, she took on a significant role as a Researcher at the South China Key Laboratory of Structural Heart Disease, where she continues to contribute to groundbreaking cardiovascular research.

🔬 CONTRIBUTIONS AND RESEARCH FOCUS ON CONGENITAL HEART DEFECTS

Dr. Yan Shi's primary research focuses on the molecular mechanisms of congenital and familial heart diseases, especially:

  • Tetralogy of Fallot (TOF)

  • Familial Dilated Cardiomyopathy (DCM)

  • Wnt signaling pathways in cardiac development

  • Single coronary artery animal models

She has successfully led and participated in several national-level projects, including:

  • SORBS2's role in familial dilated cardiomyopathy via the AKT pathway (2024-2027).

  • NOTCH1 point mutations leading to Tetralogy of Fallot (2022-2024).

  • Establishing an animal model for single coronary artery using mice (2020-2022).

🏅 IMPACT AND INFLUENCE

Dr. Yan Shi’s work has been widely recognized in the academic community. She has published several influential papers in reputable journals as the first, co-first, or corresponding author, covering:

  • Wnt signaling and cardiomyocyte differentiation

  • NOTCH1 mutations in congenital heart disease

  • Genetic polymorphisms in BVES associated with Tetralogy of Fallot

Additionally, she was a contributor to a team that won the First-Class Guangdong Natural Science Award (2020) for their research on genes regulating cardiovascular development.

📚 ACADEMIC CITES

Her published research has been cited in various genetic, developmental biology, and cardiovascular journals. Some of her notable publications include:

  • "Variants and Molecular Mechanism of NOTCH1 in Congenital Heart Disease" – Corresponding Author

  • "Novel biphasic mechanism of the canonical Wnt signaling component PYGO2 promotes cardiomyocyte differentiation" – First Author

  • "Structure and function of Pygo in organ development" – First Author

🚀 LEGACY AND FUTURE CONTRIBUTIONS

As an emerging leader in the field of genetic cardiology, Dr. Yan Shi’s legacy is shaped by her contributions to understanding the genetic underpinnings of heart disease, which hold promise for improving clinical diagnostics and therapies for congenital heart conditions. Her future work is expected to explore further genetic pathways and their therapeutic targeting, potentially leading to personalized treatments for heart diseases.

📑 NOTABLE PUBLICATIONS

"Novel biphasic mechanism of the canonical Wnt signalling component PYGO2 promotes cardiomyocyte differentiation from hUCMSCs"

Authors: Y Shi, B Qin, X Fan, Y Li, Y Wang, W Yuan, Z Jiang, P Zhu, J Chen, Y Chen, F Li, Y Wan
Journal: Cell and Tissue Research
Year: 2023

"Structure and function of Pygo in organ development dependent and independent Wnt signalling"

Authors: Y Shi, X Wu, S Zhu, H Huang, J Zhuang, H Yuan, W Yuan, P Zhu
Journal: Biochemical Society Transactions
Year: 2020

Yan Pan | Kawasaki disease | Best Researcher Award

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Mr. Yan Pan | Kawasaki disease | Best Researcher Award

Mr. Yan Pan, The First Affiliated Hospital of Yangtze University, China

Mr. Yan Pan is a distinguished pediatrician at The First Affiliated Hospital of Yangtze University, China, specializing in Kawasaki disease. He serves as Deputy Chief Physician of Pediatrics and Chief Expert of the Kawasaki Disease MDT Team. A Fellow of the Royal Society of Arts and Crafts (RSA, UK), he is Deputy Editor-in-Chief of the International Journal of Pediatrics (2023). With 10 SCI-indexed publications, he has led multiple research projects and contributed to China’s 2023 Kawasaki Disease Treatment Guidelines. Recognized with awards for pediatric research excellence, he continues to advance pediatric infectious disease diagnosis and treatment globally.

AUTHOR PROFILE

Google Scholar Profile

🎓EARLY ACADEMIC PURSUITS:

Mr. Yan Pan pursued a strong academic foundation in pediatrics, focusing on childhood diseases and immunological disorders. His passion for medical research led him to specialize in Kawasaki disease, a rare but serious pediatric illness. His early education and training laid the groundwork for his later contributions to pediatric medicine and innovative treatments.

🏥PROFESSIONAL ENDEAVORS:

Currently, Mr. Yan Pan serves as the Deputy Chief Physician of Pediatrics at The First Affiliated Hospital of Yangtze University in China. He is the Chief Expert of the Kawasaki Disease MDT Team, where he plays a crucial role in diagnosing and treating Kawasaki disease. In 2023, he was appointed Deputy Editor-in-Chief of the International Journal of Pediatrics, contributing significantly to the field through editorial leadership and research dissemination.

🔍CONTRIBUTIONS AND RESEARCH FOCUS ON KAWASAKI DISEASE:

Mr. Yan Pan has been actively involved in numerous scientific research projects, including:

  • Hosting a project for the Hubei Pediatric Medical Alliance (2021), which received an excellent completion rating.
  • Leading two research projects in Jingzhou City, one of which won third prize in the Jingzhou City Natural Science Excellent Academic Paper Award (2020).
  • Contributing to a major research project at the Wuhan Science and Technology Bureau, which is currently ongoing.
  • Collaborating with the Kawasaki Disease Center at Chang Gung Memorial Hospital, Taiwan, to advance treatment protocols and research.

His research primarily focuses on pediatric infections and immunity, particularly Kawasaki disease, aiming to enhance diagnostic accuracy and treatment efficacy.

🌍IMPACT AND INFLUENCE:

His influence extends beyond clinical practice and research. He is recognized as:

  • A Fellow of the Royal Society of Arts and Crafts (RSA), UK.
  • A China National Knowledge Infrastructure (CNKI) Evaluation Expert.
  • An Expert of the China Pharmaceutical Innovation Industry Science and Technology Service Team for Science and Technology Innovation.

His expertise has shaped clinical guidelines and treatment protocols, directly impacting the pediatric community in China and beyond.

📚ACADEMIC CITATIONS AND RECOGNITION:

  • 10 SCI-indexed articles published as first author or corresponding author.
  • Awarded “Best Researcher” in Pediatric Infection and Immunity (2023), organized by Science Father.
  • Recognized as an Excellent Scientific and Technological Worker at the Kawasaki Disease Diagnosis and Treatment Research Center in Shaanxi Province (2023).
  • Winner of the Best Outstanding Paper of the Year (2023) by Discussion of Clinical Cases Magazine.

🚀LEGACY AND FUTURE CONTRIBUTIONS:

Mr. Yan Pan’s lasting contributions to pediatric medicine include his role in compiling the “Evidence-Based Treatment Guidelines for Kawasaki Disease in Chinese Children (2023 Edition)”. His continued research and dedication to improving diagnostic and treatment methodologies ensure that his impact will be felt for generations to come.

His future focus remains on enhancing Kawasaki disease treatment, expanding research collaborations, and mentoring the next generation of pediatricians to advance medical knowledge and patient care.

🌟CONCLUSION:

Mr. Yan Pan is a leading pediatrician dedicated to advancing the diagnosis and treatment of Kawasaki disease in children. His contributions to research, clinical practice, and medical guidelines  have significantly improved pediatric healthcare. As a renowned expert and mentor , he continues to shape the future of pediatric infectious disease treatment. With numerous awards, publications, and leadership roles , his impact extends beyond China to the global medical community . Through his dedication and innovation, Mr. Yan Pan remains a driving force in ensuring better health outcomes for children worldwide.

TOP NOTABLE PUBLICATIONS

Title: Anal swab findings in an infant with COVID-19
Authors: Q Fan, Y Pan, Q Wu, S Liu, X Song, Z Xie, Y Liu, L Zhao, Z Wang, Y Zhang, …
Journal: Pediatric Investigation
Year: 2020

Title: The M235T polymorphism in the angiotensinogen gene and myocardial infarction risk: A meta-analysis
Authors: YJ Wang, Y Pan
Journal: Journal of the Renin-Angiotensin-Aldosterone System
Year: 2014

Title: Angiotensin-converting enzyme insertion/deletion polymorphism and susceptibility to Kawasaki disease: a meta-analysis
Authors: Y Pan, H Lu
Journal: African Health Sciences
Year: 2017

Title: Treatment of immunoglobulin-resistant Kawasaki disease: a Bayesian network meta-analysis of different regimens
Authors: Y Pan, Q Fan, L Hu
Journal: Frontiers in Pediatrics
Year: 2023

Title: Identification of potential core genes in immunoglobulin-resistant Kawasaki disease using bioinformatics analysis
Authors: Y Pan, Q Fan
Journal: Critical Reviews™ in Eukaryotic Gene Expression
Year: 2020

Title: Guideline for the diagnosis and treatment of incomplete Kawasaki disease in children in China
Authors: F Jiao, Y Pan, Z Du, F Deng, X Yang, H Wang, J Shen, W Xiang, Z Mu, …
Journal: BMC Pediatrics
Year: 2024

Title: The role of procalcitonin for predicting Kawasaki disease
Authors: Y Pan, Q Fan
Journal: Fetal and Pediatric Pathology
Year: 2022

Title: Clostridium symbiosum sepsis diagnosed using next-generation sequencing in a 2-year-old child: a case report
Authors: Y Pan, Q Fan
Journal: Fetal and Pediatric Pathology
Year: 2023

Title: Application of artificial intelligence in the diagnosis and treatment of Kawasaki disease
Authors: Y Pan, FY Jiao
Journal: World Journal of Clinical Cases
Year: 2024

Title: Relationship between Kawasaki disease and abdominal pain
Authors: Y Pan, FY Jiao
Journal: World Journal of Clinical Cases
Year: 2024

Gousia Mukhtar | Pediatric Cardiomyopathy | Best Researcher Award

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Gousia Mukhtar | Pediatric Cardiomyopathy | Best Researcher Award

🌟 Dr. Gousia Mukhtar is a dedicated Pediatric Cardiologist with a passion for unraveling the mysteries of young hearts. Armed with a prestigious D.M. Cardiology degree from SCTIMST, Trivandrum, she has been on an illustrious journey of healing and discovery. 🩺 Her MD in Pediatrics from SKIMS, Srinagar, laid the foundation for her deep understanding of child health.

📚 With a rich academic background, including an MBBS from Government Medical College, Srinagar, Dr. Mukhtar’s commitment to excellence shines through. 🏆 She has received accolades such as the Best Researcher Award and secured top positions in national-level quizzes, showcasing her academic prowess.

🔬 Driven by a curiosity for research, she has contributed significantly to the field of Pediatric Cardiomyopathy, presenting groundbreaking work at conferences and earning recognition. 📊 Her published studies highlight her expertise in areas like congenital heart diseases and innovative approaches to cardiac care.

👶 Dr. Gousia Mukhtar’s current role as a Postdoctoral Fellow in Pediatric Cardiology at SCTIMST reflects her dedication to advancing pediatric cardiac healthcare. 🌈 With a heart full of compassion and a mind fueled by curiosity, she continues to make valuable contributions to the well-being of young hearts.

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Education:

🎓 Dr. Gousia Mukhtar, a rising star in pediatric cardiology, completed her D.M. in Cardiology in 2021 at SCTIMST, Trivandrum, Kerala. 🏥 Prior, she earned an MD in Pediatrics in 2015 from SKIMS, Srinagar, and laid the foundation with an MBBS degree from Government Medical College, Srinagar, in 2010. 🌟 Armed with a diverse medical education, she brings a holistic perspective to her practice, combining the intricacies of pediatric care with advanced cardiac expertise. 🚀 Dr. Mukhtar’s journey reflects a commitment to lifelong learning, fostering a unique blend of compassion and clinical excellence in her pursuit of healing young hearts.

Experience:

🗓️ Dr. Gousia Mukhtar’s professional journey is a timeline of dedication and expertise. 🏥 From her current role as a Pediatric Cardiologist at SCTIMST, Trivandrum, since January 2023, to her stint as a Senior Resident in Cardiology at SKIMS, Srinagar, from March 2022 to December 2022, her commitment to healthcare shines through. 🌟 Noteworthy is her achievement of a D.M. Cardiology degree from SCTIMST, spanning from January 2019 to December 2021. 📚 Her impactful research includes publications on topics like RV outpouching, aortic stenosis, and clinical profiles of cardiomyopathy in children. 🩺 Dr. Mukhtar’s career is a testament to her passion for advancing pediatric cardiac care.

Achivements:

🏆 Dr. Gousia Mukhtar has consistently showcased her prowess, securing the third position in the PCSI National Level Quiz at the Virtual Conference in 2021. 🧠 Her achievements extend to the Zonal Level of the National Indian Society of Hematology and Blood Transfusion Quiz Competition at PGIMER, Chandigarh, in 2013, where she again clinched the third position. 🩸 Additionally, Dr. Mukhtar is equipped with expertise in emergency pediatric care, having successfully completed the Pediatric Advanced Life Support (PALS) course in 2013. 🚑 Her accolades reflect not only her academic excellence but also her commitment to staying at the forefront of medical knowledge and skills.

Publications: