Ming-Yow Hung | Interventional Cardiology | Best Researcher Award

Posted on 17/02/202517/02/2025 by Pencis

Prof. Ming-Yow Hung | Interventional Cardiology | Best Researcher Award

Prof. Ming-Yow Hung, Shuang Ho Hospital, Taipei Medical University, Taiwan

Professor Ming-Yow Hung is a distinguished cardiologist and academic based at Shuang Ho Hospital, Taipei Medical University, in Taipei, Taiwan. He earned his Doctor of Medicine degree from Chang Gung University in 1996, followed by a Master of Science and a Ph.D. in Clinical Medical Sciences from the same institution in 2007 and 2017, respectively. Since 2022, he has been serving as a Professor in the Department of Internal Medicine at Taipei Medical University. His clinical expertise encompasses coronary interventions, peripheral interventions, and echocardiography. Professor Hung has received several accolades, including the 2022 TMU Academic Research Award and recognition in “Who’s Who in Medicine and Healthcare” in 2011 and 2012. His research interests focus on the mechanisms of inflammatory cytokines in coronary spasm and the anatomical and functional changes in the left ventricle of patients with coronary spasm.

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🎓 Education:

Professor Ming-Yow Hung completed his medical education at the School of Medicine, College of Medicine, Chang Gung University, in Taoyuan, Taiwan, where he studied from September 1989 to June 1995. After earning his medical degree, he undertook an internship at Chang Gung Memorial Hospital in Taoyuan from June 1995 to June 1996. He later pursued postgraduate education, obtaining a Ph.D. in Clinical Medical Sciences from the Graduate Institute of Clinical Medical Sciences at Chang Gung University College of Medicine, where he studied from September 2007 to August 2017, further advancing his expertise in the field.

🏥Work Experience:

Professor Ming-Yow Hung began his military service as a Lieutenant General Physician in the Navy of Taiwan from August 1996 to May 1998. Afterward, he completed his residency in Internal Medicine at Chang Gung Memorial Hospital, Taoyuan, Taiwan, from July 1998 to June 2001, followed by a two-year cardiology fellowship from July 2001 to June 2003. He served as an attending cardiologist at the same hospital from July 2003 to May 2008. Since 2008, Professor Hung has been an attending cardiologist at Shuang Ho Hospital, Taipei Medical University. In academia, he progressed from Assistant Professor (2011-2017) to Associate Professor (2017-2022) and has been a Full Professor since February 2022.

🌟Professional Activities:

Professor Ming-Yow Hung has been actively involved in various professional roles throughout his career. From September 2004 to August 2005, he served on the Medical Record Management Committee at Chang Gung Memorial Hospital, Taoyuan. He was part of the Committee of Clinical Techniques and Medical Care for Clerkship Training from 2005 to 2006. He also served as the Director of the Intensive Care Unit at Shuang Ho Hospital from 2008 to 2009. Professor Hung was a faculty member at the 8th Annual Complex Cardiovascular Catheter Therapeutics Global Summit in 2012. He was the Director of Interventional Cardiology and Cardiac Cath Lab from 2014 to 2018. Additionally, he contributed to the Academic Educational Committee of the Taiwan Society of Echocardiography from 2008 to 2010.

🔬Research Interest:

Professor Ming-Yow Hung’s research interests focus on several key areas within cardiology. He specializes in interventional cardiology, particularly exploring innovative techniques and approaches in coronary and peripheral interventions. Additionally, his work emphasizes echocardiography, where he investigates advanced imaging techniques to enhance diagnostic accuracy and patient outcomes. Professor Hung is also deeply engaged in basic cardiovascular science, conducting research to better understand the underlying mechanisms of cardiovascular diseases. Through these areas of research, he aims to contribute to the advancement of both clinical practices and scientific knowledge in the field of cardiology.

🏆Honors and Awards:

Professor Ming-Yow Hung has received numerous honors and awards throughout his career. In 2001, he earned the Second Best Chart Record Award from the Department of Internal Medicine at Chang Gung Memorial Hospital. He was included in the 28th edition of Who’s Who in the World and the Who’s Who in Medicine and Healthcare (2011-2012). Notable accolades include invitations to speak at prestigious events like the Cardiology Grand Round at the University of California, San Diego, and the Complex Cardiovascular Catheter Therapeutics Global Summit. He also received multiple research awards from Taipei Medical University in 2014 and 2015, as well as recognition for his research achievements at Shuang Ho Hospital and various conferences in 2019 and 2022.

🌍Conclusion:

Professor Ming-Yow Hung is a highly accomplished cardiologist and academic, with expertise in interventional cardiology, echocardiography, and basic cardiovascular science. His extensive education, military service, and career at top medical institutions like Chang Gung Memorial Hospital and Taipei Medical University showcase his dedication to both clinical practice and research. Throughout his career, he has been recognized with numerous awards for his contributions to medicine and healthcare. His work continues to impact the field of cardiology, improving patient care and advancing scientific understanding.

Top Notable Publications

From Acute Carditis, Rheumatic Carditis, and Morphologic Cardiac Reactions to Allergic Angina, Allergic Myocardial Infarction and Kounis Syndrome: A Multidisciplinary and Multisystem Disease

Journal: Preprint

Year: 2025

Effects of statins in patients with coronary artery spasm: A nationwide population‐based study

Journal: Clinical and Translational Science

Cardio-Oncoimmunology: Cardiac Toxicity, Cardiovascular Hypersensitivity, and Kounis Syndrome

Journal: Life

Cardio-Oncology: Cardiac Toxicity, Cardiovascular Hypersensitivity, and Kounis Syndrome

Journal: Preprint

“When”, “Where”, and “How” of SARS-CoV-2 Infection Affects the Human Cardiovascular System: A Narrative Review

Journal: Preprint

Outcomes of Atrioventricular Node Ablation and Pacing in Patients with Heart Failure and Atrial Fibrillation: From Cardiac Resynchronization Therapy to His Bundle Pacing

Journal: Journal of Cardiovascular Development and Disease

Year: 2023

Coronary Artery Spasm-Related Heart Failure Syndrome: Literature Review

Journal: International Journal of Molecular Sciences

Year: 2023

Relationship between Inflammation and Vasospastic Angina

Journal: Medicina

Year: 2023

The Effect of Long COVID-19 Infection and Vaccination on Male Fertility; A Narrative Review

Journal: Vaccines

Year: 2022

Apolipoprotein (a)/Lipoprotein(a)-Induced Oxidative-Inflammatory α7-nAChR/p38 MAPK/IL-6/RhoA-GTP Signaling Axis and M1 Macrophage Polarization Modulate Inflammation-Associated Development of Coronary Artery Spasm

Journal: Oxidative Medicine and Cellular Longevity

Year: 2022

Atsuko Nakayama | Cardiac Rehabilitation | Best Researcher Award

Posted on 17/02/202517/02/2025 by Pencis

Dr. Atsuko Nakayama | Cardiac Rehabilitation | Best Researcher Award

Dr. Atsuko Nakayama, Sakakibara Heart Institute, Japan

Dr. Atsuko Nakayama, M.D., Ph.D., is a renowned cardiologist and expert in cardiovascular medicine and rehabilitation at the Sakakibara Memorial Hospital in Japan. She serves as the Director of the Department of Cardiovascular Medicine, Head of the Cardiac Rehabilitation Unit, and Director of the Comprehensive Support Center for Heart Disease. Dr. Nakayama is a pioneer in integrating AI and telemedicine into cardiac care and rehabilitation, with a focus on personalized treatment plans and wearable technologies. She holds leadership roles in several professional organizations and contributes to national policies on cardiovascular disease as a member of Japan’s Ministry of Health, Labour, and Welfare.

AUTHOR PROFILE

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🎓EARLY ACADEMIC PURSUITS:

Dr. Atsuko Nakayama’s academic journey began with a strong foundation in medicine, culminating in a Doctorate from the prestigious University of Tokyo in March 2012. Her passion for cardiovascular medicine was evident from early on, and her academic excellence set the stage for a career that would merge clinical practice with cutting-edge research. Her early studies laid the groundwork for her future focus on medical device development, telemedicine, and rehabilitation in the cardiovascular field.

🏥PROFESSIONAL ENDEAVORS:

Dr. Nakayama currently holds multiple leadership roles at the Sakakibara Memorial Hospital, where she serves as the Director of the Department of Cardiovascular Medicine, Head of the Cardiac Rehabilitation Unit, and Director of the Comprehensive Support Center for Heart Disease. Her leadership extends beyond her hospital, as she has been appointed as the representative of the Heart Disease Work-Life Balance Support Network in December 2024. Additionally, since June 2024, Dr. Nakayama has been a member of the Cardiovascular Disease Control Promotion Council under Japan’s Ministry of Health, Labour, and Welfare.

Her professional endeavors reflect a commitment to both the clinical and policy aspects of cardiovascular health. She has been at the forefront of integrating new technologies and rehabilitation approaches into routine care, improving patient outcomes through innovation.

🔬CONTRIBUTIONS AND RESEARCH FOCUS ON CARDIAC REHABILITATION:

Dr. Nakayama’s research has focused on advancing the integration of technology in cardiovascular medicine, particularly through the use of artificial intelligence (AI) and telemedicine. She is recognized for her work in developing AI-driven diagnostic tools, wearable technologies, and remote cardiac rehabilitation programs. Her research also spans exercise physiology, aortic aneurysms, hypertrophic cardiomyopathy, and healthcare quality assessment.

Her pioneering work has enabled the development of AI-assisted patient monitoring systems and personalized treatment plans, revolutionizing cardiac rehabilitation. Dr. Nakayama has been instrumental in incorporating AI and big data analytics into cardiovascular care, allowing for predictive and preventive interventions in heart disease.

🌍IMPACT AND INFLUENCE:

Dr. Nakayama’s contributions extend well beyond the hospital and laboratory. Through her leadership in various professional organizations, including serving as the chair of the JCS-JJC committee of the Japanese Circulation Society since 2022, she has influenced the direction of cardiovascular research and practice in Japan. Her role in national policy-making, including her position on the Cardiovascular Disease Control Promotion Council, allows her to shape public health initiatives and promote AI-powered healthcare solutions on a national scale.

Her influence has been recognized by prestigious awards, including the “STI for SDGs” Award from the Japan Science and Technology Agency in 2024, recognizing her groundbreaking work in remotecardiac rehabilitation

📚ACADEMIC CITATIONS:

Dr. Nakayama’s research has been widely cited in the fields of telemedicine, AI in healthcare, and cardiovascular rehabilitation. Her work has paved the way for numerous studies exploring the use of technology to improve patient outcomes. As a fellow of both the Japanese Circulation Society and the American Heart Association, her research continues to have a significant impact on the scientific community.

🔮LEGACY AND FUTURE CONTRIBUTIONS:

Dr. Nakayama’s legacy is one of innovation, leadership, and compassionate care. Her contributions to AI-driven healthcare, particularly in the field of cardiology, have set new standards in patient care and rehabilitation. As she continues her work in AI-assisted diagnostics and rehabilitation, her future contributions promise to further revolutionize cardiovascular medicine and improve the lives of millions of patients.

Her ongoing efforts to shape policies, integrate cutting-edge technologies into clinical practice, and advocate for better healthcare systems ensure that Dr. Nakayama’s impact will be felt for years to come, leaving a lasting legacy in the world of medicine.

🌟CONCLUSION:

Dr. Atsuko Nakayama is a trailblazer in the field of cardiovascular medicine, combining clinical expertise with groundbreaking research in AI and telemedicine. Her leadership at Sakakibara Memorial Hospital, coupled with her contributions to national health policies, has made a lasting impact on cardiac care and rehabilitation in Japan. Through her innovative use of technology, she continues to improve patient outcomes and shape the future of healthcare. Dr. Nakayama’s dedication to advancing both medicine and healthcare systems ensures that her work will inspire generations of clinicians and researchers.

TOP NOTABLE PUBLICATIONS:

A national survey of career development according to gender and subspecialties among cardiologists in Japan
Authors: M. Shimbo, A. Nakayama, N. Fukue, T. Taniguchi, Y. Kobayashi
Journal: PLoS ONE
Year: 2025

Predicting Heart Rate at the Anaerobic Threshold Using a Machine Learning Model Based on a Large-Scale Population Dataset
Authors: A. Nakayama, T. Iwata, H. Sakuma, K. Kashino, H. Tomoike
Journal: Journal of Clinical Medicine
Year: 2025

Impact of Long-Term Exercise-Based Cardiac Rehabilitation in Patients With Chronic Heart Failure ― A Systematic Review and Meta-Analysis
Authors: S. Yamamoto, M. Okamura, Y. Akashi, S. Makita, M. Isobe
Journal: Circulation Journal
Year: 2024
Citations: 2

Sex Differences in Cardiovascular Disease-Related Hospitalization and Mortality in Japan ― Analysis of Health Records From a Nationwide Claim-Based Database, the Japanese Registry of All Cardiac and Vascular Disease (JROAD)
Authors: S. Noma, K. Kato, T. Otsuka, K. Maemura, Y.T. Tsukada
Journal: Circulation Journal
Year: 2024

Litao Guo | Cardiac Rehabilitation | Best Researcher Award

Posted on 17/02/202517/02/2025 by Pencis

Prof. Litao Guo | Cardiac Rehabilitation | Best Researcher Award

Prof. Litao Guo, The First Affiliated Hospital of Xi’an Jiaotong University, Xi’an, China

Prof. Litao Guo is a Deputy Director and Associate Chief Physician at The First Affiliated Hospital of Xi’an Jiaotong University, Xi’an, China. With over 18 years of experience in intensive care medicine, he specializes in cardiopulmonary resuscitation (CPR), ECMO therapy, and critical patient management. Prof. Guo is also an expert in intelligent simulation teaching for emergency skills training. His research includes advanced ECMO treatments and innovative CPR training methods using intelligent simulation platforms. He has published 16 research papers, contributing significantly to critical care medicine and improving patient outcomes in high-risk medical situations.

AUTHOR PROFILE

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🎓EARLY ACADEMIC PURSUITS:

Prof. Litao Guo embarked on his academic journey in intensive care medicine, where he spent more than 18 years developing his expertise. From a resident to an associate chief physician, he gained valuable experience and hands-on knowledge in managing critically ill patients. Prof. Guo has also served as a master tutor, fostering the next generation of healthcare professionals, particularly in cardiopulmonary resuscitation (CPR) and ECMO treatment. This foundation in intensive care provided him with a deep understanding of patient management and critical interventions.

💼PROFESSIONAL ENDEAVORS:

Currently, Prof. Guo serves as the Deputy Director and Associate Chief Physician at The First Affiliated Hospital of Xi’an Jiaotong University in Xi’an, China. His daily responsibilities include overseeing the treatment and management of critically ill patients, particularly those requiring advanced life-saving procedures such as ECMO and CPR. He plays a pivotal role in shaping clinical practices, guiding patient care, and contributing to the advancement of intensive care medicine. His leadership is integral to the hospital’s focus on improving patient outcomes in high-stakes medical situations.

🔬CONTRIBUTIONS AND RESEARCH FOCUS ON CARDIAC REHABILITATION:

Prof. Guo is widely recognized for his research on intelligent simulation teaching and training methods, particularly in CPR. His work involves leveraging cutting-edge technology to enhance the teaching and practical skills of medical staff in emergency procedures. He has been instrumental in developing an intelligent simulation platform to train teams in effective CPR techniques, emphasizing team coordination, division of labor, and the standing position during resuscitation efforts. Additionally, his research delves into the management of ECMO therapy, focusing on treating complications such as massive airway bleeding with early clamping and advanced intervention measures.

🌍IMPACT AND INFLUENCE:

Prof. Guo’s research and clinical contributions have had a significant impact on improving outcomes for critically ill patients. His work on ECMO combined with advanced airway management has been especially groundbreaking, offering new insights and techniques to reduce mortality rates. His intelligent simulation teaching platform is transforming the way first responders and healthcare professionals are trained, ensuring they are equipped with the best skills to save lives. Prof. Guo’s publications, including 16 relevant research papers, have gained widespread recognition within the medical community.

📚ACADEMIC CITATIONS:

Prof. Guo has published 16 research papers, many of which focus on innovative approaches to CPR and ECMO. His scholarly work has contributed to the growing body of knowledge in intensive care medicine, particularly in areas that directly affect patient survival in critical care settings. These publications are frequently cited by other researchers, underscoring the importance of his work in advancing medical practice.

🔮LEGACY AND FUTURE CONTRIBUTIONS:

Prof. Guo is dedicated to further advancing intensive care medicine through both his clinical practice and research endeavors. His focus on innovative training techniques and treatment protocols, such as ECMO and CPR management, ensures that future healthcare providers will be well-equipped to manage complex and life-threatening situations. His legacy will be one of continuous improvement in the fields of sepsis, resuscitation, and critical care, with lasting effects on the healthcare system and patient care outcomes.

🌟CONCLUSION:

Prof. Litao Guo’s work in intensive care medicine, particularly in cardiopulmonary resuscitation (CPR) and ECMO therapy, has had a profound impact on improving patient care and outcomes in critical settings. His pioneering research on intelligent simulation platforms for emergency training is revolutionizing medical education, ensuring better preparedness among healthcare teams. With over 18 years of experience and 16 published papers, his contributions continue to shape the field. Prof. Guo’s commitment to advancing both clinical practice and medical education ensures that his legacy will inspire future generations of healthcare professionals.

TOP NOTABLE PUBLICATIONS

Exploration of cardiopulmonary resuscitation teamwork training for maternal cardiac arrest using the SimMan intelligent simulation platform: A simulation teaching study

Authors: Zhang, Ruirui; Liu, Yu; Zhang, Mingming; Bai, Hongliang; Guo, Litao

Journal: Health Science Reports

Year: 2024

Regional Practice Variation and Outcomes in the Standard Versus Accelerated Initiation of Renal Replacement Therapy in Acute Kidney Injury (STARRT-AKI) Trial: A Post Hoc Secondary Analysis

Authors: Vaara, Suvi T.; Neto, Ary Serpa; Bellomo, Rinaldo; Yang, Yang; Padayachee, Laven

Journal: Critical Care Explorations

Year: 2024

Lingyan Chen | Cardiovascular Diseases | Best Researcher Award

Posted on 17/02/202517/02/2025 by Pencis

Dr. Lingyan Chen | Cardiovascular Diseases | Best Researcher Award

Dr. Lingyan Chen, Wenzhou Medical university, China

Dr. Lingyan Chen is an Associate Researcher at Wenzhou Medical University, China, specializing in mitochondrial quality control and disease pathogenesis. She holds a Ph.D. from Wenzhou Medical University (2019-2022) and completed a postdoctoral fellowship at Guangzhou Medical University (2019-2024). Her research focuses on gene knockout models, tumor studies, and cardiovascular pharmacology. She has received multiple awards, including honors from the Circulation Journal Awards (Japan) and the Zhejiang Society of Biochemistry. With extensive experience in molecular biology techniques, Dr. Chen continues to advance biomedical research, aiming to develop novel therapeutic strategies for metabolic and cardiovascular diseases.

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🎓EARLY ACADEMIC PURSUITS:

Dr. Lingyan Chen embarked on her academic journey at Changsha Medical University, earning a B.Sc. degree (2006-2009). She then pursued a M.Sc. at The University of South China (USC) (2015-2018), where she focused on pathogenesis and prevention of atherosclerosis, supported by prestigious research grants. She completed her Ph.D. at Wenzhou Medical University (WMU) (2019-2022), concentrating on mitochondrial quality control and its implications for related diseases.

🏥PROFESSIONAL ENDEAVORS:

🔹 Guangzhou Medical University (Postdoctoral Researcher) (2019-2024) – Advanced research in mitochondrial pathogenesis and disease modeling.
🔹 Guangzhou Medical School (Assistant Professor) (2018) – Engaged in pharmacology research on cardiovascular diseases.
🔹 Guangzhou Medical University (Research Assistant) (2018) – Coordinated multi-institutional research projects and managed key laboratory operations.
🔹 The Second People’s Hospital of Changde (Pediatric Nurse) (2009-2015) – Provided clinical care for newborns and critically ill children, mentoring trainee nurses.

🔬CONTRIBUTIONS AND RESEARCH FOCUS ON CARDIOVASCULAR DISEASES:

Dr. Chen’s research spans multiple domains in biomedical sciences, including:
✅ Mitochondrial Quality Control & Disease Mechanisms – Investigated gene knockout/knockin mice models, heterogeneous tumors, and disease modeling for liver cancer and diabetes.
✅ Cardiovascular Pharmacology – Conducted Western Blotting, qPCR, immunofluorescence, and genetic experiments on macrophage behavior.
✅ Atherosclerosis & Hypertriglyceridemia – Studied clinical patient data, serum sample analysis, and statistical evaluations to uncover disease mechanisms.

🌍IMPACT AND INFLUENCE:

Dr. Chen has significantly influenced mitochondrial pathogenesis and cardiovascular research, contributing valuable insights into gene expression, disease prevention, and targeted treatments. Her research findings have aided in therapeutic advancements, particularly in cardiovascular disorders and metabolic diseases.

📚ACADEMIC CITES & LEGACY:

Dr. Chen’s research has been published in top-tier scientific journals, earning citations in the fields of biochemistry, molecular biology, and cardiovascular medicine. Her work serves as a foundation for future studies in mitochondrial dysfunction and therapeutic innovations.

🚀FUTURE CONTRIBUTIONS & VISION:

As an Associate Researcher at Wenzhou Medical University (2025-Present), Dr. Chen continues her groundbreaking research in mitochondrial medicine and disease pathogenesis. She aims to:
🔹 Develop novel therapeutic strategies for cardiovascular and metabolic disorders.
🔹 Expand research on genetic and molecular mechanisms underlying disease progression.
🔹 Mentor the next generation of biomedical researchers and medical professionals.

🏆AWARDS AND HONORS:

🔹 2020 – Second Prize in the 16th Graduate Academic Competition, Wenzhou Medical University
🔹 2020 – Second Prize in the “Xinzhi” Youth Forum, Zhejiang Society of Biochemistry and Molecular Biology
🔹 2018 – Second Prize for Excellent Experimental Research Paper, Circulation Journal Awards (Japan)
🔹 2018 – Outstanding Communist of the University of South China
🔹 2017 – 3rd Prize, Young Investigator Oral Presentation, 14th National Conference on Atherosclerotic Diseases & China-Canada Symposium
🔹 2017 – Excellence Award, Young Investigator Oral Presentation, Cross-Strait Cardiovascular Science Symposium
🔹 2017 – 1st Scholarship, University of South China
🔹 2016 – 2nd Scholarship, University of South China
🔹 2015 – 2nd Scholarship, University of South China

🌟CONCLUSION:

Dr. Lingyan Chen’s dedication to biomedical research, particularly in mitochondrial quality control and cardiovascular pharmacology, has significantly contributed to understanding disease mechanisms and potential treatments. Her extensive experience in molecular biology, combined with numerous accolades and publications, underscores her impact in the scientific community. As she continues her research at Wenzhou Medical University, Dr. Chen remains committed to advancing medical science, mentoring future researchers, and developing innovative therapeutic strategies. Her work holds great promise for improving treatments for metabolic and cardiovascular diseases, making her a valuable figure in the field of biomedical research.

TOP NOTABLE PUBLICATIONS

Inhibition of mitochondrial OMA1 ameliorates osteosarcoma tumorigenesis

Authors: Chen, Lingyan; Chen, Dejian; Pan, Yiming; Zhang, Dawei; Xia, Xiaodan

Journal: Cell Death and Disease

Year: 2024

Ciclopirox drives growth arrest and autophagic cell death through STAT3 in gastric cancer cells

Authors: Chen, Lingyan; Chen, Dejian; Li, Jiwei; Lu, Xiaoang; Lu, Bin

Journal: Cell Death and Disease

Year: 2022

MicroRNA-377 inhibits atherosclerosis by regulating triglyceride metabolism through the DNA methyltransferase 1 in apolipoprotein E-knockout mice

Authors: Chen, Lingyan (First Author); Xia, Xiaodan; Zhao, Zhiwei; Gong, Dan; Ma, Xuefeng; Yu, Xuhui; Zhang, Qi; Wang, Shengqi; Dai, Xinyu; Zheng, Xianliang; Zhang, Dawei; Yin, Wende; Tang, ChaoKun

Journal: Circulation Journal

Year: 2018

Myocardin suppression increases lipid retention and atherosclerosis via downregulation of ABCA1 in vascular smooth muscle cells

Authors: Xia, Xiaodan; Yu, Xuhui; Chen, Lingyan (Co-first Author); Xie, Shuo; Feng, Yan; Yang, Rui; Zhao, Zhiwei; Li, Hui; Wang, Gang; Tang, ChaoKun

Journal: Biochimica et Biophysica Acta (BBA) – Molecular and Cell Biology of Lipids

Year: 2021

Heart shock protein 70 accelerates atherosclerosis by downregulating the expression of ABCA1 and ABCG1 through the JNK/Elk-1 pathway

Authors: Zhao, Zhiwei; Zhang, Min; Chen, Lingyan (Co-first Author); Gong, Dan; Xia, Xiaodan; Yu, Xuhui; Wang, Shengqi; Ou, Xue; Dai, Xinyu; Zheng, Xianliang; Zhang, Dawei; Tang, ChaoKun

Journal: Biochimica et Biophysica Acta

Year: 2018

Puerarin promotes ABCA1-mediated cholesterol efflux and decreases cellular lipid accumulation in THP-1 macrophages

Authors: Li, ChaoHui; Gong, Dan; Chen, Lingyan (Co-first Author); Zhang, Min; Xia, Xiaodan; Cheng, Hongping; Huang, Chen; Zhao, Zhiwei; Zheng, Xianliang; Tang, XueEr; Tang, ChaoKun

Journal: European Journal of Pharmacology

Year: 2017

IL-8 negatively regulates ABCA1 expression and cholesterol efflux via upregulating miR-183 in THP-1 macrophage-derived foam cells

Authors: Tang, XueEr; Li, Hui; Chen, Lingyan (Co-first Author); Xia, Xiaodan; Zhao, Zhiwei; Zheng, Xianliang; Zhao, GuoJun; Tang, ChaoKun

Journal: Cytokine

Year: 2019

Xuhui Lin | Recent Advancements | Best Researcher Award

Posted on 12/02/202512/02/2025 by Pencis

Mr. Xuhui Lin | Recent Advancements| Best Researcher Award

Mr. Xuhui Lin, The Alan Turing Institute, United Kingdom

Mr. Xuhui Lin is a researcher in sustainable urban systems , specializing in transportation resilience, graph theory, and AI-driven infrastructure analysis . He is currently pursuing an MPhil/PhD at University College London (UCL) , focusing on enhancing urban road network resilience under flooding . Lin has worked with leading institutions, including The Alan Turing Institute, UCL, University of Georgia, and UC Berkeley . His research spans digital twins, smart cities, and AI applications in urban planning . With multiple high-impact publications and top academic distinctions , he is dedicated to shaping sustainable, data-driven urban solutions.

Author Profile

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🎓 Education:

Mr. Xuhui Lin is currently pursuing an MPhil/PhD in Sustainable Construction at University College London (UCL) , focusing on enhancing urban transportation resilience through graph dynamic systems under flooding (2023–Present). He previously earned an MSc in Digital Innovation in Built Asset Management from UCL (2022–2023) , ranking in the top 1% with distinction. Lin holds a Bachelor of Design in Architecture from the University of Sydney (2015–2018), graduating 1st Class Honors, top 1%. He also attended UCL Summer School (2017) and briefly studied Commerce at The University of Sydney (2014).

💼 Work Experience:

Mr. Xuhui Lin is a Researcher under the Enrichment Scheme at The Alan Turing Institute (2024–2025) , applying graph theory and synchronization models to analyze urban transportation resilience. Simultaneously, he works as a Research Assistant at DAFNI , developing digital twins to assess congestion risks during floods. He previously contributed to Visual Large Language Models at the University of Georgia and applied graph network algorithms to biological data at Southern Medical University . As an Algorithm Engineer at UC Berkeley , he refined 3D AI-powered robot interfaces. Lin also worked at UrbanX Lab & Alibaba (2018–2022), developing digital twins for urban regeneration. His past roles include urban planning at Tsinghua University, flood resilience studies at UCL, and point-of-interest analysis for commercial optimization. He has a strong interdisciplinary background, integrating AI, transportation systems, and urban planning into resilient, data-driven solutions.

🚀Research Interests:

Mr. Xuhui Lin’s research focuses on urban resilience, transportation networks, and digital innovation in the built environment . His work integrates graph theory, synchronization dynamics, and field theory to enhance urban transportation resilience under extreme events like flooding . He is passionate about data-driven urban planning, employing AI, machine learning, and large-scale simulations to optimize infrastructure performance. Lin explores multimodal urban systems, developing digital twins to assess congestion risks and predict transportation disruptions. His interdisciplinary approach extends to biomedical engineering , where he applies network analysis to biological data for drug development. Additionally, he investigates human-AI interactions, refining 3D interfaces for robotics and smart cities. With expertise in spatial cognition, computational urban design, and digital asset management, Lin aims to bridge the gap between technology and sustainable city planning, fostering smarter, more adaptive urban environments for the future.

🔬 Research Experience:

Mr. Xuhui Lin has an extensive research background spanning urban resilience, digital innovation, AI-driven infrastructure analysis, and biomedical engineering . At The Alan Turing Institute, he applies graph theory to assess transportation network complexity and enhance urban mobility under disruptions . As a Research Assistant at DAFNI, he developed digital twins to evaluate congestion risks during floods . His work at University of Georgia focused on Visual Large Language Models (VLLMs) for urban spatial analysis, while at Southern Medical University, he explored biological information networks for drug discovery . Lin also contributed to 3D user interfaces for AI-powered robotics at UC Berkeley and conducted transport resilience studies at UCL. His expertise in machine learning, graph neural networks, and digital asset management enables cutting-edge research at the intersection of smart cities, AI, and infrastructure resilience, driving sustainable urban transformation.

🏆 Awards and Honors:

Mr. Xuhui Lin has received numerous prestigious awards and honors for his outstanding contributions to urban resilience, AI-driven infrastructure analysis, and digital innovation . He graduated Top 1% with Distinction in both his MSc at UCL and Bachelor of Design in Architecture at the University of Sydney . His research excellence earned him a position as a Researcher under the Enrichment Scheme at The Alan Turing Institute . He has also received multiple academic scholarships and grants for his work in graph theory, transportation resilience, and digital twins . Lin’s contributions to high-impact journals such as Reliability Engineering & System Safety and IEEE Transactions on Intelligent Transportation Systems further highlight his scholarly impact . His multidisciplinary expertise, spanning AI, urban planning, and biomedical research, has solidified his reputation as a leading researcher in smart city innovation and infrastructure resilience.

🔍 Conclusion:

Mr. Xuhui Lin’s research embodies a cutting-edge fusion of urban resilience, AI, and network dynamics . His work advances transportation sustainability, digital twins, and smart city innovations , contributing to real-world solutions for flood-prone urban networks . With extensive research collaborations, high-impact publications, and algorithmic advancements , Lin continues to push the boundaries of data-driven urban infrastructure. His commitment to sustainable and intelligent urban planning ensures his work remains impactful and forward-thinking . As cities evolve, his expertise will be crucial in designing resilient, adaptive, and efficient urban systems for the future.

Top Notable Publications

Title: Automated building information modeling compliance check through a large language model combined with deep learning and ontology
Authors: N Chen, X Lin, H Jiang, Y An
Journal: Buildings
Year: 2024

Title: Sandpile-simulation-based graph data model for MVD generative design of shield tunnel lining using information entropy
Authors: Y An, X Lin, H Li, Y Wang
Journal: Advanced Engineering Informatics
Year: 2023

Title: Assessing dynamic congestion risks of flood-disrupted transportation network systems through time-variant topological analysis and traffic demand dynamics
Authors: X Lin, Q Lu, L Chen, I Brilakis
Journal: Advanced Engineering Informatics
Year: 2024

Title: Rethinking the city resilience: COM-B model-based analysis of healthcare accessing behaviour changes affected by COVID-19
Authors: J Yan, Z Fang, L Chen, J Tang, Q Lu, X Lin
Journal: Journal of Housing and the Built Environment
Year: 2024

Title: RESHAPE: Rapid forming and simulation system using unmanned aerial vehicles for architectural representation
Authors: X Lin, R Muslimin
Journal: CAADRIA Proceedings
Year: 2019

Title: Development and Validation of a Novel Model to Discriminate Idiosyncratic Drug‐Induced Liver Injury and Autoimmune Hepatitis
Authors: Y Wang, X Lin, Y Sun, J Liu, J Li, Q Tian, F Guo, X Hu, L Wang, P Li, …
Journal: Liver International
Year: 2025

Title: Benchmarking best practice of digital built asset management
Authors: X Lin, P Liu, J Yan, X Chen
Journal: Digital Built Asset Management
Year: 2024

Title: Enhancing Urban Flood Response: Traffic Flow Prediction with Field Theory-Inspired Physics-Informed Graph Neural Network
Authors: X Lin, Q Lu, T Broyd, T Cheng, X Zhang, T Erfani, TH Tran
Journal: –
Year: 2024

Title: Developing a context-based bounded centrality approach of street patterns in flooding: a case study of London
Authors: X Lin, Q Lu, N Gunn, S Sølvsten
Journal: UCL
Year: 2023

Yingqiang Du | Myocardial Infarction | Best Researcher Award

Posted on 12/02/202512/02/2025 by Pencis

Dr. Yingqiang Du | Myocardial Infarction | Best Researcher Award

Dr. Yingqiang Du, Department of Cardiology, The Affiliated Suzhou Hospital of Nanjing Medical University; Suzhou Municipal Hospital; Gusu School, Nanjing Medical University, China

Dr. Yingqiang Du is a renowned cardiology researcher at The Affiliated Suzhou Hospital of Nanjing Medical University, Suzhou Municipal Hospital, and Gusu School, Nanjing Medical University, China. His research focuses on myocardial infarction and ischemic heart disease, exploring inflammation, fibrosis, metabolic remodeling, and novel therapeutic strategies. As the first or corresponding author of multiple high-impact publications, he has significantly contributed to cardiovascular medicine. His work bridges basic and clinical research, influencing treatment advancements and patient care. With ongoing projects funded by prestigious grants, Dr. Du continues to drive innovation in cardiology, shaping the future of cardiovascular health research.

AUTHOR PROFILE

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📚 EARLY ACADEMIC PURSUITS:

Dr. Yingqiang Du began his academic journey with a strong foundation in medical sciences, focusing on cardiology and cardiovascular research. His early education provided him with a deep understanding of human physiology, pathology, and the complexities of ischemic heart disease. With a keen interest in myocardial infarction and its underlying mechanisms, he pursued specialized training and research, laying the groundwork for his future contributions to the field.

🏥 PROFESSIONAL ENDEAVORS:

Currently, Dr. Du is affiliated with The Affiliated Suzhou Hospital of Nanjing Medical University, Suzhou Municipal Hospital, and Gusu School, Nanjing Medical University. As a researcher and academic professional, he has taken on significant responsibilities in both clinical and experimental cardiology. His work bridges the gap between theoretical research and practical applications, ensuring that scientific findings translate into improved patient care.

🔬 CONTRIBUTIONS AND RESEARCH FOCUS ON MYOCARDIAL INFARCTION:

Dr. Du’s research primarily centers on myocardial infarction and ischemic heart disease. His studies delve into various aspects, including:

The role of inflammation and fibrosis in cardiovascular conditions.
The impact of environmental factors, such as micro(nano)plastics, on heart disease.
Novel therapeutic approaches involving bioactive compounds like resveratrol and muscone.
The involvement of metabolic remodeling and inflammasome activation in aging cells. His extensive work provides crucial insights into the prevention, diagnosis, and treatment of cardiac disorders.

🌟 IMPACT AND INFLUENCE:

Dr. Du’s research has had a profound impact on the field of cardiology. His studies have contributed to a better understanding of the molecular mechanisms of myocardial infarction and fibrosis, paving the way for new treatment modalities. His findings have influenced clinical practices and have been referenced in various medical and scientific discussions worldwide.

📖 ACADEMIC CITES:

As an established researcher, Dr. Du has authored multiple high-impact publications in reputed journals, including:

Journal of Hazardous Materials
Clinical and Translational Medicine
Experimental and Therapeutic Medicine
Bioengineered
American Journal of Translational Research These publications, where he serves as either the first or corresponding author, reflect his credibility and expertise in the field. His work has been widely cited by peers, demonstrating its relevance and significance.

🏆 LEGACY AND FUTURE CONTRIBUTIONS:

Dr. Du’s contributions to cardiology are paving the way for future breakthroughs in cardiovascular medicine. His research findings are not only enhancing current medical knowledge but also inspiring upcoming researchers to explore novel therapeutic strategies. Moving forward, his work is expected to contribute significantly to:

The development of innovative drug treatments for myocardial infarction.
The formulation of preventive measures against ischemic heart disease.
The exploration of new molecular pathways for better cardiovascular health. His ongoing commitment to research excellence ensures that his legacy will continue to shape the future of cardiology.

🌍CONCLUSION:

Dr. Yingqiang Du is a distinguished researcher whose groundbreaking contributions to cardiology have significantly advanced the understanding of myocardial infarction and ischemic heart disease. His extensive studies on inflammation, fibrosis, and metabolic remodeling have influenced both clinical practices and future research directions. With multiple high-impact publications and ongoing projects, his work continues to shape modern cardiovascular medicine.

TOP NOTABLE PUBLICATION

Title: Exposure to polyethylene terephthalate micro(nano)plastics exacerbates inflammation and fibrosis after myocardial infarction by reprogramming the gut and lung microbiota and metabolome

Authors: X., Gu, Xin, Z., Zhang, Zhixuan, L., Zhao, Lin, … X., Wang, Xiaoyan, Y., Du, Yingqiang

Journal: Journal of Hazardous Materials

Year: 2025

Ling Chen | Cardiac Surgery | Best Researcher Award

Posted on 12/02/202512/02/2025 by Pencis

Dr. Ling Chen | Cardiac Surgery | Best Researcher Award

Dr. Ling Chen, Fujian union hospital, China

Dr. Ling Chen is a renowned cardiac surgeon at Fujian Medical University Affiliated Union Hospital, China. Specializing in aortic dissection, heart valve diseases, and congenital heart defects, Dr. Chen has made significant contributions to cardiovascular surgery. With a strong background in clinical research, Dr. Chen has published in top journals, including Nature Communications. Their work focuses on improving surgical outcomes through innovative techniques like valve-sparing procedures and minimally invasive interventions. Dedicated to advancing cardiac care, Dr. Chen continues to explore novel treatments and biomarkers for cardiovascular diseases, shaping the future of heart surgery in China and beyond.

AUTHOR PROFILE

Orcid Profile

🎓 EARLY ACADEMIC PURSUITS:

Dr. Ling Chen’s journey in medicine began at Fujian Medical University, where they pursued a Bachelor’s Degree in Clinical Medicine (2012-2017) . Their deep interest in cardiac surgery led them to earn a Master’s Degree in Surgery (2017-2020) , under the mentorship of Prof. Mingqiang Kang. Driven by a passion for advanced surgical techniques, Dr. Chen completed a Doctorate in Surgery (2020-2023) , under Prof. Liangwan Chen, focusing on groundbreaking cardiovascular research.

🏥 PROFESSIONAL ENDEAVORS:

Currently serving as a Resident Physician in the Department of Cardiac Surgery (August 2023 – Present) at Fujian Medical University Affiliated Union Hospital, Dr. Chen specializes in:
✔ Aortic Dissection
✔ Aneurysms
✔ Heart Valve Diseases
✔ Coronary Heart Disease
✔ Congenital Heart Defects

Dr. Chen is actively involved in clinical surgeries and research, aiming to improve surgical outcomes through minimally invasive techniques and innovative treatments.

🔬 CONTRIBUTIONS AND RESEARCH FOCUS ON CARDIAC SURGERY:

Dr. Chen’s research bridges clinical application and scientific discovery, significantly contributing to the field of cardiac surgery and cardiovascular medicine. Their key research areas include:
✅ Pathogenesis of Aortic Dissection – Investigating the underlying mechanisms to improve early diagnosis and treatment.
✅ Factors Influencing Long-Term Prognosis of Minimally Invasive Surgery for Congenital Heart Disease – Enhancing post-surgical outcomes for pediatric and adult patients.

During their tenure at Beijing University School of Basic Medical Sciences (June 2022 – June 2023) , under the mentorship of Prof. Zheng Lemin, Dr. Chen worked on:
✔ Screening and Validation of Novel Biomarkers for Cardiovascular Diseases – Identified potential biomarkers for early cardiovascular disease detection.
✔ Gene Function in Heart Development and Disease – Discovered two new genes linked to heart developmental defects, improving genetic insights into congenital heart conditions.

🌍 IMPACT AND INFLUENCE:

Dr. Chen’s work has far-reaching implications in cardiac surgery and precision medicine:
🔹 Advancing diagnostic tools for cardiovascular diseases using genetic research.
🔹 Improving minimally invasive surgical procedures to enhance patient recovery.
🔹 Integrating biomarker research into clinical applications for early disease detection.

Their dedication to bridging research and clinical practice is helping shape the future of cardiovascular medicine.

📖 ACADEMIC CITES AND PUBLICATIONS:

Dr. Chen’s groundbreaking research has been featured in leading journals, including:
📄 “Propensity Score Matching Analysis of Valve-Sparing Versus Aortic Root Replacement in Type A Aortic Dissection Patients” (Nature Communications, 2025)

This study provides critical insights into optimizing surgical strategies for complex cardiac conditions.

🏆 LEGACY AND FUTURE CONTRIBUTIONS:

Dr. Ling Chen is committed to transforming cardiovascular healthcare through innovation. Their vision for the future includes:
✔ Developing novel surgical approaches to treat heart diseases more effectively.
✔ Expanding research on genetic and molecular mechanisms of cardiovascular disorders.
✔ Enhancing patient outcomes through personalized medicine and advanced diagnostics.

With a strong foundation in surgery, research, and clinical expertise, Dr. Chen continues to pioneer advancements in cardiac surgery, ensuring a lasting impact in the medical field.

🌍CONCLUSION:

Dr. Ling Chen’s dedication to cardiac surgery and research has greatly advanced treatments for aortic dissection, heart valve diseases, and congenital heart defects 🫀. Their expertise in minimally invasive techniques and commitment to improving patient outcomes have led to groundbreaking contributions in the field. With prestigious publications , innovative surgical techniques , and a passion for discovery, Dr. Chen continues to shape the future of cardiovascular medicine . Their work not only enhances surgical precision but also paves the way for new advancements , ensuring better healthcare for patients worldwide.

TOP NOTABLE PUBLICATION

“Propensity score matching analysis of valve-sparing versus aortic root replacement in type A aortic dissection patients”:

Authors: Ling Chen, Yichao Pan, Huaijian Zhang, Yi Chen, Chunsheng Wang, Zhihuang Qiu, Heng Lu, Liangwan Chen.

Journal: Nature Communications

Year: 2025